A device for cutting tissue, the device comprising a first tube having a side window; a second tube positioned within the first tube, the second tube having a side window and being movable within the first tube; a third tube positioned within the second tube, the third tube having a side window and being movable within the second tube; and a needle insertable within the second tube, the needle housing a suture. The windows in the first, second, and third tubes are alignable with each other. The invention includes methods for the cutting and suturing of tissue by using the device.

Patent
   5947983
Priority
Mar 16 1998
Filed
Mar 16 1998
Issued
Sep 07 1999
Expiry
Mar 16 2018
Assg.orig
Entity
Large
345
30
all paid
1. A device for cutting tissue within a body lumen, said device comprising:
a first tube extending from a proximal portion to a distal portion, wherein, in an operative position, the distal portion is located within the body lumen adjacent to the tissue to be cut; the first tube having a side window in the distal portion thereof;
a second tube extending from a proximal portion to a distal portion, wherein the distal portion is moveably mounted within the distal portion of the first tube, said second tube having a second side window which, when the first and second tubes are in an alignment with respect to one another, faces the first side window so that an interior of the second tube is open to an exterior of the first tube; and
a third tube extending from a proximal portion to a distal portion, wherein the distal portion is moveably mounted within the distal portion of the second tube, said third tube having a third side window, wherein said third window is alignable with said first and second windows.
15. A method for cutting tissue from a body lumen, said method comprising the steps of:
providing a device comprising:
a first tube extending from a proximal portion to a distal portion, wherein, in an operative position, the distal portion is located within the body lumen adjacent to the tissue to be cut; the first tube having a side window in the distal portion thereof;
a second tube extending from a proximal portion to a distal portion, wherein the distal portion is moveably mounted within the distal portion of the first tube, said second tube having a second side window which, when the first and second tubes are in an alignment with respect to one another, faces the first side window so that an interior of the second tube is open to an exterior of the first tube; and
a vacuum tube extending from a proximal portion to a distal portion, wherein the distal portion is moveably mounted within the distal portion of the second tube, said vacuum tube having a third side window, wherein said third window is alignable with said first and second windows;
inserting said device into the body lumen so that the first window is positioned adjacent to a portion of tissue to be cut;
aligning said first, second and third windows to form an opening in said device extending from an exterior of said first tube to an interior of said vacuum tube;
sucking the portion of tissue to be cut into said opening;
moving said second tube with respect to said first tube to reduce the size of said opening and grasp the portion of tissue to be cut; and
moving said vacuum tube with respect to said first and second tubes to cut the grasped tissue.
25. A method for cutting a portion of tissue protruding from a body lumen, said method comprising the steps of:
providing a device comprising:
a first tube extending from a proximal portion to a distal portion, wherein, in an operative position, the distal portion is located within the body lumen adjacent to the tissue to be cut; the first tube having a side window in the distal portion thereof;
a second tube extending from a proximal portion to a distal portion, wherein the distal portion is moveably mounted within the distal portion of the first tube, said second tube having a second side window which, when the first and second tubes are in an alignment with respect to one another, faces the first side window so that an interior of the second tube is open to an exterior of the first tube; and
a third tube extending from a proximal portion to a distal portion, wherein the distal portion is moveably mounted within the distal portion of the second tube, said third tube having a third side window, wherein said third window is alignable with said first and second windows;
inserting said device into the body lumen so that the first window is positioned adjacent to a portion of tissue to be cut;
aligning said first and second windows to form an opening in said device extending from an exterior of said first tube to an interior of said second tube;
positioning said opening over the portion of tissue to be cut so that the portion of tissue extends into the opening;
moving said second tube with respect to said first tube to grasp the tissue received within the opening;
positioning said window in said third tube over the grasped tissue; and
moving said third tube with respect to said first and second tubes to cut the grasped tissue from the body lumen.
35. A method for cutting tissue from a body lumen, said method comprising the steps of:
providing a device comprising:
a first tube extending from a proximal portion to a distal portion, wherein, in an operative position, the distal portion is located within the body lumen adjacent to the tissue to be cut; the first tube having a side window in the distal portion thereof;
a second tube extending from a proximal portion to a distal portion, wherein the distal portion is moveably mounted within the distal portion of the first tube, said second tube having a second side window which, when the first and second tubes are in an alignment with respect to one another, faces the first side window so that an interior of the second tube is open to an exterior of the first tube; and
a third tube extending from a proximal portion to a distal portion, wherein the distal portion is moveably mounted within the distal portion of the second tube, said third tube having a third side window, wherein said third window is alignable with said first and second windows;
a tissue grasper extending from a proximal portion to a distal portion, wherein the distal portion is moveably mounted within said third tube,
inserting said device into the body lumen so that the first window is positioned adjacent to a portion of tissue to be cut;
aligning said first, second and third windows to form an opening in said device extending from an exterior of said first tube to an interior of said third tube;
extending said tissue grasper through said opening;
grasping the portion of tissue to be cut with said tissue grasper;
pulling the portion of tissue to be cut into said opening;
moving said second tube with respect to said first tube to reduce the size of said opening and grasp the portion of tissue to be cut; and
moving said third tube with respect to said first and second tubes to cut the grasped tissue.
2. The device of claim 1, wherein said third window has at least one cutting edge.
3. The device of claim 1, wherein said third tube is a vacuum tube through which negative pressure may be applied to draw tissue into the first, second and third windows.
4. The device of claim 1, further comprising a tissue grasper within said third tube, said tissue grasper for grasping and drawing tissue into the first, second and third windows.
5. The device of claim 1, further comprising a needle insertable within said second tube, said needle housing a suture.
6. The device of claim 5, wherein said needle is substantially helical.
7. The device of claim 6, wherein said second tube has a substantially helical groove in an inner surface thereof, said helical groove being adapted to receive said needle.
8. The device of claim 5, wherein said suture comprises an anchor portion, which when penetrated through a portion of tissue, resists removal therefrom and thus maintains the suture in a desired position.
9. The device of claim 8, wherein said anchor portion comprises an elastic material.
10. The device of claim 9, wherein said elastic material is selected from the group consisting of a polymeric material, stainless steel and nitinol.
11. The device of claim 8, wherein said anchor portion has a pointed tip.
12. The device of claim 8, wherein during insertion of the needle through the tissue, the anchor member is maintained in a storage position within the needle and, when released from the needle, the anchor member expands to an anchor position.
13. The device of claim 1, wherein said first, second and third windows are elongated in a longitudinal direction of said first, second and third tubes, respectively.
14. The device of claim 1, wherein said first, second and third windows are elongated in the circumferential direction of said first, second and third tubes, respectively.
16. The method of claim 15, wherein said step of inserting said device into the body lumen occurs via a natural body orifice.
17. The method of claim 15, further comprising the steps of:
inserting a needle into said second tube, said needle housing a suture;
pushing said needle through said grasped tissue;
withdrawing said needle from the grasped tissue, said step of withdrawing leaving said suture through the grasped tissue; and
tightening said suture to seal a wound resulting from the cutting of the grasped tissue.
18. The method of claim 17, wherein said vacuum tube is removed from said second tube before said needle is inserted into said second tube.
19. The method of claim 17, wherein:
said needle is substantially helical;
said second tube has a substantially helical groove formed in an inner surface thereof, said helical groove being adapted to receive said needle;
said step of pushing said needle through the grasped tissue includes the steps of:
placing said needle in said groove, and rotating said needle in a first direction about its longitudinal axis to advance the needle towards the grasped tissue and to push the needle through the grasped tissue; and
said step of withdrawing said needle from the grasped tissue includes the step of rotating said needle in a second direction about a longitudinal axis thereof, said second direction being opposite said first direction.
20. The method of claim 15, wherein said window in said vacuum tube has at least one cutting edge.
21. The method of claim 15, wherein said step of moving of said second tube includes the step of rotating said second tube relative to said first tube.
22. The method of claim 15, wherein said step of moving said second tube includes the step of moving said second tube relative to the first tube along a longitudinal axis of the second tube.
23. The method of claim 15, wherein said step of moving said vacuum tube includes the step of rotating said vacuum tube relative to the second tube.
24. The method of claim 15, wherein said step of moving said vacuum tube includes the step of moving said vacuum tube relative to the second tube along a longitudinal axis of the vacuum tube.
26. The method of claim 25, wherein said step of inserting said device into the body lumen occurs via a natural body orifice.
27. The method of claim 25, further comprising the steps of:
inserting a needle into said second tube, said needle housing a suture;
pushing said needle through said grasped tissue;
withdrawing said needle from the grasped tissue, said step of withdrawing leaving said suture through the grasped tissue; and
tightening said suture to seal a wound resulting from the cutting of the grasped tissue.
28. The method of claim 25, wherein said third tube is removed from said second tube before said needle is inserted into said second tube.
29. The method of claim 25, wherein:
said needle substantially helical;
said second tube has a substantially helical groove formed in an inner surface thereof, said helical groove being adapted to receive said needle;
said step of pushing said needle through the grasped tissue includes the steps of:
placing said needle in said groove, and rotating said needle in a first direction about its longitudinal axis to advance the needle towards the grasped tissue and to push the needle through the grasped tissue; and
said step of withdrawing said needle from the grasped tissue includes the step of rotating said needle in a second direction about a longitudinal axis thereof, said second direction being opposite said first direction.
30. The method of claim 25, wherein said window in said third tube has at least one cutting edge.
31. The method of claim 25, wherein said step of moving of said second tube includes the step of rotating said second tube relative to said first tube.
32. The method of claim 25, wherein said step of moving said second tube includes the step of moving said second tube relative to the first tube along a longitudinal axis of the second tube.
33. The method of claim 25, wherein said step of moving said third tube includes the step of rotating said third tube relative to the second tube.
34. The method of claim 25, wherein said step of moving said third tube includes the step of moving said third tube relative to the second tube along a longitudinal axis of the third tube.

The present invention relates to a device and method for cutting tissue, and more specifically, to grasping, cutting, and stitching tissue within a body lumen.

When tissue surrounding a body lumen becomes cancerous or otherwise diseased, it is often necessary to remove the diseased tissue for analysis or disposal. Conventional devices and methods for such tissue removal often require open surgery to access the diseased tissue. Because open surgery is an intrusive procedure with many undesired side-effects, less invasive procedures for internal tissue removal are desired.

Recently, tissue cutters have been developed for in-situ (i.e., laparoscopic, endoscopic, etc.) tissue removal. U.S. Pat. Nos. 5,643,304 and 5,527,332, both incorporated herein by reference, describe such cutters. One limitation of these cutters, however, is that they do not provide an effective mechanism for grasping tissue before cutting. As a result, it is often difficult to accurately remove localized diseased tissue without also removing a substantial amount of the surrounding tissue. Moreover, conventional cutters do not provide a means for suturing the tissue from which the diseased tissue has been removed. It is therefore not possible to use such devices alone for the removal of the full-wall thickness of a body lumen without leakage from the lumen (of blood, feces, etc.).

The present invention is directed to a device and method for cutting tissue from any body lumen such as, for example, veins, arteries, the stomach, intestines, esophagus and bowels.

In one aspect, the present invention provides a device for cutting tissue comprising a plurality of tubes insertable within each other. Each of the tubes has a window therein to facilitate the grasping and cutting of tissue within a body lumen. The device preferably includes a needle for suturing the lumen after cutting and removal of tissue therefrom.

In one embodiment, the device of the present invention includes first, second and third tubes, each having a side window therein. The first tube extends from a proximal portion to a distal portion and has a side window in the distal portion. In an operative position, the distal portion of the first tube is located within a body lumen adjacent to the tissue to be cut. The second tube extends from a proximal portion to a distal portion, wherein the distal portion is moveably mounted within the distal portion of the first tube. The second tube has a second side window which, when the first and second tubes are in an alignment with respect to one another, faces the first side window so that an interior of the second tube is open to an exterior of the first tube. The third tube extends from a proximal portion to a distal portion, wherein the distal portion is moveably mounted within the distal portion of the second tube. The third tube has a third side window, wherein the third window is alignable with the first and second windows.

In another aspect, the present invention provides a method for cutting tissue from a body lumen, comprising the steps of providing the device as described above, wherein the third tube is a vacuum tube; inserting the device into the body lumen so that the first window is positioned adjacent to a portion of tissue to be cut; aligning the windows in each of the first, second and vacuum tubes to form an opening in the device which extends from an exterior of the first tube to an interior of the vacuum tube; sucking a portion of tissue into the opening; moving the second tube with respect to the first tube to reduce the size of the opening and to grasp the portion of tissue to be cut; and moving the third tube with respect to the first and second tubes to cut the grasped portion of tissue.

In yet another aspect, the present invention provides a method for cutting a portion of tissue protruding from a body lumen, comprising the steps of inserting a device as described above into the body lumen; inserting the device into the body lumen so that the first window is positioned adjacent to the portion of tissue to be cut; aligning the windows in the first and second tubes to form an opening in the device extending from an exterior of the first tube to an interior of the second tube; positioning the opening over the protrusion; moving the second tube with respect to the first tube to grasp the body lumen wall adjacent to the protrusion; positioning the window in the third tube over the grasped protrusion; and moving the third tube with respect to the first and second tubes to cut the protrusion from the body lumen.

In yet another aspect, the present invention provides a method for cutting a portion of tissue from a body lumen using a tissue grasper. In this aspect, the device includes a tissue grasper within the third tube. The method comprises the steps of inserting the device into the body lumen so that the first window is positioned adjacent to a portion of tissue to be cut; aligning the first, second and third windows to form an opening in the device extending from an exterior of the first tube to an interior of the third tube; extending the tissue grasper through the opening; grasping the portion of tissue to be cut with the tissue grasper; pulling the portion of tissue to be cut into the opening; moving the second tube with respect to the first tube to reduce the size of the opening and grasp the portion of tissue to be cut; and moving the third tube with respect to the first and second tubes to cut the grasped tissue.

FIG. 1A illustrates a first portion of a device according to the present invention.

FIG. 1B illustrates a second portion of the device of FIG. 1A.

FIG. 1C illustrates a third portion of the device of FIG. 1A.

FIGS. 2A-2E illustrate a method for cutting and removing tissue from a body lumen wall, in accordance with the present invention.

FIG. 2F illustrates a portion of a body lumen that has been cut and sutured.

FIG. 3 illustrates an embodiment of the present invention that includes a tissue grasper.

The present invention provides for the removal of tissue from a body lumen without resorting to open surgery and allows for the identification of tissue desired for removal from a body lumen. As accurate, localized cutting of that tissue and preferably, in-situ suturing of the remaining tissue is possible, the full thickness of a body lumen wall can be extracted without resulting in excessive bleeding or leakage from the lumen.

FIGS. 1A-1C show a device according to the present invention. As shown in FIG. 1A, a grasper portion of a device 100 includes a first tube 110 and a second tube 120, wherein the second tube 120 is movable within the first tube 110. The first and second tubes 110, 120 include windows 111 and 121, respectively, which may be aligned with each other as shown in FIG. 1A by moving the second tube 120 axially relative to the first tube 110 or by rotating the first and second tubes 110, 120 relative to one another. A third tube 130, as shown in FIG. 1B, is moveably mountable within the second tube 120 and includes a third window 131.

The third window 131 preferably includes at least one cutting edge 132 which may be formed as part of the third window 131 by machining, for example. The cutting edge 132 is preferably positioned so that, when the windows 111, 121 and 131 are aligned to expose the interior of the tube 130 to the environment outside the device 100, the cutting edge 132 extends perpendicular to a direction of relative movement between the third tube 130 and the first and second tubes 110, 120. That is, the cutting edge 132 is positioned so that when a cutting movement is performed, the cutting edge 132 moves from a first side of the opening 121, across opening 121, to a second side thereof. For example, if the third tube 130 is rotatable relative to the second tube 120, the cutting edge 132 would preferably extend parallel to the axis of the tubes 110, 120 and 130. However, if the tubes 110, 120 and 130 are moveable axially relative to one another, the cutting edge 132 would preferably extend circumferentially around a portion of the third tube 130.

The windows 111, 121 and 131 are of any suitable shape such as, for example, rectangular, circular, or oval. Moreover, the windows 111, 121 and 131 may extend in a longitudinal or circumferential direction, the choice of which depends on the shape of the tissue to be removed and the shape and depth of the cut to be made.

The device 100 is used, for example, to cut tissue from the side wall of a body lumen. In this embodiment, third tube 130 is a vacuum tube such that when device 100 is inserted into body lumen 211 and the windows in the first, second and vacuum tubes are aligned, tissue from lumen 211 is sucked into the vacuum tube as shown in FIG. 2A. Second tube 120 is thereafter moved with respect to first tube 110 to pinch the tissue against the edges of the windows 111 and 121 to grasp the tissue that has been sucked into vacuum tube 130. Vacuum tube 130 is then moved with respect to the second tube 120, thereby cutting and removing the grasped tissue with cutting edge 132, as shown in FIG. 2B. This aspect of the present invention is particularly well-adapted to the removal of full-wall thickness sections of a body lumen.

To facilitate the immediate suturing of the cut edges of the lumen wall 211 after, for example, the full-wall thickness cutting and removal of diseased tissue, the third tube 130 is removed from the second tube 120 (FIG. 2C) and a needle 140 is inserted into the second tube 120 (FIG. 2D). Alternatively, the third tube 130 remains within the second tube 120 while the needle 140 advances within the second tube 120. The needle 140 is inserted into the second tube 120 before the lumen wall is released by the first and second tubes 110 and 120, respectively. As shown in FIG. 1C, the needle 140 has proximal and distal ends 141 and 142, respectively, and a central bore 143, which houses the suture 145. The distal end 142 preferably includes a sharpened tip suitable for piercing tissue. The needle 140, which optionally includes a side opening 144 for the introduction of the suture 145 into the central bore 143, is mounted on a push bar 150 or the like for positioning and rotating the needle 140 within the second tube 120.

In use, the needle 140 is inserted through the grasped portion of body lumen wall by any suitable means. For example, it is preferred that the needle 140 be in the shape of a helix as shown in FIG. 1C. In this case, the second tube 120 preferably has a helical groove 122 in its inner surface adapted to receive the needle 140 such that the needle 140 is advanced through the second tube 120 and the grasped portion of body lumen side wall 211 by placing the needle 140 in the groove 122 and rotating the needle 140 to advance the needle 140 towards the distal end 125 of the second tube 120, as shown in FIG. 2D. The needle 140 may, for example, be manipulated by a flexible push bar 150, a distal end of which is attached to the needle 140 while a proximal end of the push bar 150 is coupled to an actuator (not shown) accessible to the user.

Once the needle 140 has been pushed through the grasped portion of lumen wall 211, it is withdrawn while leaving the suture 145 in place, as shown in FIG. 2E. If the needle 140 is in the shape of a helix, its withdrawal is achieved, for example, by rotating the needle 140 in a direction opposite that by which it was inserted so that the needle 140 moves away from the distal end 125 of the second tube 120. As shown in FIG. 1C, the suture 145 preferably includes an anchor portion 146 which may comprise an elastic material such as a polymeric material, a suitable biocompatible suture material, or a metallic material such as stainless steel or nitinol, for example. When the suture 145 is maintained within the needle 140, the anchor portion 146 is compressed by the outer wall of the central bore 143. When the suture 145 is pushed out of the needle 140, however, the anchor portion 146 expands under its spring bias into a desired shape selected to anchor the suture 145 against the grasped tissue. For example, the anchor portion 146 has an arrowhead configuration as shown in FIG. 1C. Alternatively, rather than being compressed within the needle 140, the anchor portion 146 may be held against the distal end 142 of needle 140 to form a sharpened tip suitable for piercing tissue. Before the needle 140 is withdrawn from the grasped portion of body lumen 211, the anchor portion 146 is extended away from the distal end 142 of the needle 140 by any suitable means, such as by applying pressure to the suture 145.

The suture 145 appears as shown in FIG. 2E after the needle 140 is withdrawn. The suture 145 is thereafter tightened by any suitable method. For example, a grasper as known in the art may be inserted into the second tube 120 to grasp and tighten the suture 145. The tightened suture 145 is secured by any suitable method, such as by tying off its free end or by crimping a suture termination element 147 onto its free end. FIG. 2F shows such a tightened suture over a cut portion of a body lumen wall 211. After the suture 145 is secured, the wall of body lumen 120 is released from the first and second tubes, 110 and 120, respectively, which are thereafter withdrawn from the body lumen.

The device 100 is also used, for example, to cut a protrusion extending from the side of a body lumen using the method illustrated in FIGS. 2A-2F. It is not necessary, however, that the third tube 130 be a vacuum tube for this purpose so long as the protrusion extends far enough away from the body lumen side wall 211 to facilitate insertion into third tube 130 for cutting.

The tubes 110, 120 and 130 are catheters, for example, that extend from outside of the body to the location within a body lumen from which tissue is to be removed, thus allowing for the easy manipulation of each of the tubes by a physician. The manipulation of the tubes 110, 120 and 130 is also suitable to laparoscopic techniques. As such, these tubes are made of a flexible material, as is known in the art. A portion 133 of the third tube 130, however, is preferably a rigid material such as stainless steel to allow the cutting edge 132 to be an integral part of the third tube 130. In this case, the rigid portion 133 is attached to a flexible portion 134 of the third tube 130 by any suitable means, such as by an interlocking joint. Alternatively, the third tube 130 is made of a single, flexible material to which the cutting edge 132 is added. The tubes 110, 120 and 130 are of any suitable size that is limited only by the inner diameter of body lumen into which the tubes are inserted.

The tubes 110, 120 and 130 are introduced into the body by any suitable means. It is preferred, however, that the device of the present invention be inserted into the body in association with an endoscope (e.g., within a working channel of an endoscope or over the exterior surface of an endoscope), which allows for the in-situ identification of diseased tissue. Once the endoscope is positioned to a target location within a body lumen, the device 100 is extended from the endoscope working channel to grasp, cut and remove diseased tissue. Alternatively, the device 100 is inserted into a body lumen without the use of an endoscope. In this latter case, fluoroscopic or similar techniques may be used to view and position the device 100 during use.

Any embodiment of the present invention optionally includes a tissue grasper 160 within the third tube 130, as shown in FIG. 3. As is known in the art, the tissue grasper grabs tissue with, for example, a pair of jaws, 161. Use of the tissue grasper 160 is preferred where the third tube 130 is not a vacuum tube. In this situation, the cutting and stitching of tissue or protrusions from body lumen walls occurs by the methods as herein described and illustration, except that the grasped tissue is pulled into the third tube by the tissue grasper 160 rather than by the action of vacuum.

The present invention provides a device and method for the minimally-invasive grasping, cutting and removal of diseased tissue from within a body lumen. Those with skill in the art may recognize various modifications to the embodiments of the invention described and illustrated herein. Such modifications are meant to be covered by the spirit and scope of the appended claims.

Solar, Matthew S., Kratsch, Peter K.

Patent Priority Assignee Title
10016194, Jan 25 2011 iSuturing, LLC Devices and methods for continuous surgical suturing
10045871, May 07 2004 USGI Medical, Inc. Apparatus for manipulating and securing tissue
10058321, Mar 05 2015 ANCORA HEART, INC Devices and methods of visualizing and determining depth of penetration in cardiac tissue
10080677, Aug 27 2001 Boston Scientific Scimed, Inc. Satiation devices and methods
10092286, May 27 2015 Covidien LP Suturing loading unit
10092402, Jun 13 2002 Ancora Heart, Inc. Devices and methods for heart valve repair
10098773, Apr 26 2004 Boston Scientific Scimed, Inc. Restrictive and/or obstructive implant for inducing weight loss
10149677, Mar 14 2009 VasoStitch, Inc. Vessel access and closure device
10245024, Jun 03 2014 Covidien LP Stitching end effector
10245061, Mar 16 2004 Covidien LP Treatment method including tissue occlusion device
10285836, Oct 10 2003 Boston Scientific Scimed, Inc. Systems and methods related to gastro-esophageal implants
10299796, Oct 03 2005 Boston Scientific Scimed, Inc Endoscopic plication devices and methods
10314571, Dec 11 2012 Howmedica Osteonics Corp. Systems for soft tissue repair
10368862, Nov 10 2008 Boston Scientific Scimed, Inc. Multi-fire stapling methods
10441302, Apr 17 2012 A-BASE KORLATOLT FELELOSSEGU TARSASAG Manipulator for grasping tissue
10485567, Mar 16 2004 Boston Scientific Scimed, Inc. Endoluminal treatment method and associated surgical assembly
10492815, Mar 16 2004 LUMENR, LLC ; Boston Scientific Scimed, Inc Endoluminal treatment method and associated surgical assembly
10517580, Dec 16 2009 LUMENR, LLC,; Boston Scientific Scimed, Inc Multi-lumen-catheter retractor system for a minimally invasive, operative gastrointestinal treatment
10531869, Dec 16 2009 LUMENR, LLC ; Boston Scientific Scimed, Inc Tissue retractor for minimally invasive surgery
10537238, Dec 16 2009 Boston Scientific Scimed, Inc. Substantially rigid and stable endoluminal surgical suite for treating a gastrointestinal lesion
10537315, Dec 16 2009 LUMENR, LLC ; Boston Scientific Scimed, Inc Multi-lumen-catheter retractor system for a minimally-invasive, operative gastrointestinal treatment
10537456, Jul 18 2007 Boston Scientific Scimed, Inc. Endoscopic implant system and method
10542987, Feb 06 2008 Ancora Heart, Inc. Multi-window guide tunnel
10548582, Dec 16 2009 LUMENR, LLC ; Boston Scientific Scimed, Inc Multi-lumen-catheter retractor system for a minimally-invasive, operative gastrointestinal treatment
10588489, Dec 16 2009 LUMENR, LLC ; Boston Scientific Scimed, Inc Endoluminal system and method for gastrointestinal treatment
10588504, Dec 16 2009 LUMENR, LLC ; Boston Scientific Scimed, Inc Multi-lumen-catheter system for a minimally-invasive treatment
10595711, Dec 16 2009 LUMENR, LLC ; Boston Scientific Scimed, Inc System for a minimally-invasive, operative gastrointestinal treatment
10595841, Dec 16 2009 LUMENR, LLC ; Boston Scientific Scimed, Inc Multi-lumen-catheter retractor system for a minimally-invasive, operative gastrointestinal treatment
10610227, Jan 31 2001 Rex Medical, L.P. Apparatus and method for resectioning gastro-esophageal tissue
10624741, Jun 13 2002 Ancora Heart, Inc. Delivery devices and methods for heart valve repair
10625047, Jan 20 2009 Ancora Heart, Inc. Anchor deployment devices and related methods
10667914, Nov 18 2016 ANCORA HEART, INC Myocardial implant load sharing device and methods to promote LV function
10675033, Jan 31 2001 Rex Medical, L.P. Apparatus and method for resectioning gastro-esophageal tissue
10716464, Dec 16 2009 Boston Scientific Scimed, Inc. Endoluminal device with retractor system
10751045, Jan 25 2011 iSuturing, LLC Suture stitches for continuous surgical suturing
10758116, Dec 16 2009 Boston Scientific Scimed, Inc; LUMENR, LLC System for a minimally-invasive, operative gastrointestinal treatment
10799234, May 27 2015 Covidien LP Suturing loading unit
10806510, Oct 19 2012 Minerva Surgical, Inc Medical systems and methods
10842482, Jan 25 2011 iSuturing, LLC Devices and methods for continuous surgical suturing
10898328, Jun 13 2002 Ancora Heart, Inc. Devices and methods for heart valve repair
10912553, May 27 2010 Howmedica Osteonics Corp. Apparatus and methods for Achilles tendon repair
10966701, Dec 16 2009 LUMENR, LLC ; Boston Scientific Scimed, Inc Tissue retractor for minimally invasive surgery
10966708, Jun 03 2014 Covidien LP Stitching end effector
10980529, Mar 05 2015 Ancora Heart, Inc. Devices and methods of visualizing and determining depth of penetration in cardiac tissue
10980973, May 12 2015 ANCORA HEART, INC Device and method for releasing catheters from cardiac structures
11045341, May 07 2004 USGI Medical, Inc. Apparatus for manipulating and securing tissue
11071534, Dec 30 2016 Boston Scientific Scimed, Inc. System for a minimally-invasive treatment within a body lumen
11122970, Dec 16 2009 LUMENR, LLC ; Boston Scientific Scimed, Inc Substantially rigid and stable endoluminal surgical suite for treating a gastrointestinal lesion
11129672, Apr 04 2019 Covidien LP Tissue resecting device including an articulatable cutting member
11202627, Nov 10 2008 Boston Scientific Scimed, Inc. Multi-fire stapling systems and methods for delivering arrays of staples
11241560, Mar 18 2017 Boston Scientific Scimed, Inc System for a minimally-invasive treatment within a body lumen
11272836, Dec 16 2009 LUMENR, LLC ; Boston Scientific Scimed, Inc Substantially rigid and stable endoluminal surgical suite for treating a gastrointestinal lesion
11284879, Dec 13 2018 HOWMEDICA OSTEONICS CORP Systems for soft tissue repair
11330976, Dec 16 2009 LUMENR, INC ; Boston Scientific Scimed, Inc Substantially rigid and stable endoluminal surgical suite for treating a gastrointestinal lesion
11576800, Jun 14 2019 Low risk, reversible, weight loss procedure
11633203, Apr 17 2012 A-BASE KORLATOLT FELELOSSEGU TARSASAG Manipulator for grasping tissue
11653972, Oct 19 2012 Minerva Surgical, Inc. Medical systems and methods
11660138, Oct 19 2012 Minerva Surgical, Inc. Medical systems and methods
11672524, Jul 15 2019 ANCORA HEART, INC Devices and methods for tether cutting
11832789, Dec 13 2019 Boston Scientific Scimed, Inc. Devices, systems, and methods for minimally invasive surgery in a body lumen
11883626, Jun 27 2019 Boston Scientific Scimed, Inc. Detection of an endoscope to a fluid management system
11950778, May 21 2010 Boston Scientific Scimed, Inc. Tissue-acquisition and fastening devices and methods
11964112, May 12 2015 Ancora Heart, Inc. Device and method for releasing catheters from cardiac structures
11992180, Dec 18 2009 Boston Scientific Scimed, Inc. Endoluminal device with retractor system
11992194, Dec 16 2009 Boston Scientific Scimed, Inc. Substantially rigid and stable endoluminal surgical suite for treating a gastrointestinal lesion
12059138, Dec 16 2009 Boston Scientific Scimed, Inc. System for a minimally-invasive, operative gastrointestinal treatment background
12082813, Feb 06 2008 Ancora Heart, Inc. Multi-window guide tunnel
12089830, Dec 16 2009 Boston Scientific Scimed, Inc. Multi-lumen-catheter retractor system for a minimally-invasive, operative gastrointestinal treatment
12102316, Mar 05 2015 Ancora Heart, Inc. Devices and methods of visualizing and determining depth of penetration in cardiac tissue
12178463, Aug 05 2005 Boston Scientific Scimed, Inc. Endoluminal treatment method and associated surgical assembly including tissue occlusion device
6328752, Oct 31 1995 Smith & Nephew, Inc. Method for positioning a surgical instrument relative to a surgical handpiece
6398795, Nov 30 2000 Boston Scientific Scimed, Inc Stapling and cutting in resectioning for full thickness resection devices
6478791, Jun 23 1998 AMS Research Corporation Tuck and fold fascia shortening for incontinence
6478805, Apr 16 1999 NuVasive, Inc System for removing cut tissue from the inner bore of a surgical instrument
6517566, May 11 1998 SURGICAL CONNECTIONS, INC Devices and methods for treating e.g. urinary stress incontinence
6558400, May 30 2001 Ethicon Endo-Surgery, Inc Obesity treatment tools and methods
6626917, Oct 26 2000 Edwards Lifesciences AG Helical suture instrument
6716222, Nov 30 2000 Boston Scientific Scimed, Inc Stapling and cutting in resectioning for full thickness resection devices
6740098, May 11 1998 SURGICAL CONNECTIONS, INC Surgical stabilizer devices and methods
6746460, Aug 07 2002 Ethicon Endo-Surgery, Inc Intra-gastric fastening devices
6773440, Jul 02 2002 Ethicon Endo-Surgery, Inc Method and device for use in tissue approximation and fixation
6902570, Jun 08 2001 IP VERWERTUNGS GMBH Device and method for connecting hollow organs and/or sealing wall defects in hollow organs
6986776, Jun 28 2001 Suturing apparatus, method and system
6994715, Aug 07 2002 Ethicon Endo-Surgery, Inc Intra-gastric fastening devices
7083629, May 30 2001 Ethicon Endo-Surgery, Inc Overtube apparatus for insertion into a body
7097650, Oct 14 2003 Ethicon Endo-Surgery, Inc System for tissue approximation and fixation
7175638, Apr 16 2003 Ethicon Endo-Surgery, Inc Method and devices for modifying the function of a body organ
7211094, Nov 05 2002 Ethicon Endo-Surgery, Inc Magnetic anchoring devices
7214233, Aug 30 2002 Ethicon Endo-Surgery, Inc Methods and devices for maintaining a space occupying device in a relatively fixed location within a stomach
7220237, Oct 23 2002 Ethicon Endo-Surgery, Inc Method and device for use in endoscopic organ procedures
7220266, May 19 2000 C R BARD, INC Tissue capturing and suturing device and method
7229428, Oct 23 2002 Ethicon Endo-Surgery, Inc Method and device for use in endoscopic organ procedures
7261722, Dec 20 2001 REX MEDICAL, L P Apparatus and method for treating gastroesophageal reflux disease
7288099, May 30 2001 Ethicon Endo-Surgery, Inc Obesity treatment tools and methods
7288101, May 30 2001 Ethicon Endo-Surgery, Inc Obesity treatment tools and methods
7306614, May 30 2001 Ethicon Endo-Surgery, Inc Overtube apparatus for insertion into a body
7334718, Nov 30 2000 Boston Scientific Scimed, Inc Stapling and cutting in resectioning for full thickness resection devices
7347863, May 07 2004 SOLAR CAPITAL LTD , AS SUCCESSOR AGENT Apparatus and methods for manipulating and securing tissue
7361180, May 07 2004 SOLAR CAPITAL LTD , AS SUCCESSOR AGENT Apparatus for manipulating and securing tissue
7399304, Mar 02 2000 C R BARD, INC Endoscopic tissue apposition device with multiple suction ports
7416554, Dec 11 2002 SOLAR CAPITAL LTD , AS SUCCESSOR AGENT Apparatus and methods for forming and securing gastrointestinal tissue folds
7503922, May 30 2001 Ethicon Endo-Surgery, Inc Obesity treatment tools and methods
7510559, May 30 2001 Ethicon Endo-Surgery, Inc Obesity treatment tools and methods
7520884, May 07 2004 SOLAR CAPITAL LTD , AS SUCCESSOR AGENT Methods for performing gastroplasty
7571729, Mar 09 2004 SOLAR CAPITAL LTD , AS SUCCESSOR AGENT Apparatus and methods for performing mucosectomy
7588582, Jun 13 2002 ANCORA HEART, INC Methods for remodeling cardiac tissue
7601159, Sep 30 2004 SOLAR CAPITAL LTD , AS SUCCESSOR AGENT Interlocking tissue anchor apparatus and methods
7618426, Dec 11 2002 SOLAR CAPITAL LTD , AS SUCCESSOR AGENT Apparatus and methods for forming gastrointestinal tissue approximations
7621925, Sep 30 2004 SOLAR CAPITAL LTD , AS SUCCESSOR AGENT Needle assembly for tissue manipulation
7628821, Apr 08 2002 Boston Scientific Scimed, Inc Obesity treatment method
7637918, Aug 16 2004 Zimmer Spine, Inc. Helical suturing device
7666193, Jun 13 2002 GUIDED DELIVERY SYSTEMS, INC Delivery devices and methods for heart valve repair
7703459, Mar 09 2004 SOLAR CAPITAL LTD , AS SUCCESSOR AGENT Apparatus and methods for mapping out endoluminal gastrointestinal surgery
7704264, Dec 12 2003 SOLAR CAPITAL LTD , AS SUCCESSOR AGENT Apparatus and methods for forming and securing gastrointestinal tissue folds
7708181, Mar 18 2008 Boston Scientific Scimed, Inc Endoscopic stapling devices and methods
7708684, Feb 27 2004 Ethicon Endo-Surgery, Inc Methods and devices for reducing hollow organ volume
7721932, Mar 18 2008 Boston Scientific Scimed, Inc Endoscopic stapling devices and methods
7727249, May 03 2006 Indiana University Research & Technology Corporation Methods and apparatuses for reshaping the esophagus and other body lumens
7731654, May 13 2005 Merit Medical Systems, Inc Delivery device with viewing window and associated method
7731727, Apr 26 2006 LSI Solutions, Inc.; LSI Solutions, Inc Medical instrument to place a pursestring suture, open a hole and pass a guidewire
7736374, Mar 01 2005 SOLAR CAPITAL LTD , AS SUCCESSOR AGENT Tissue manipulation and securement system
7744609, Oct 21 1999 Edwards Lifesciences Corporation Minimally invasive mitral valve repair method and apparatus
7744613, Jun 25 1999 SOLAR CAPITAL LTD , AS SUCCESSOR AGENT Apparatus and methods for forming and securing gastrointestinal tissue folds
7753858, Jul 27 2004 ANCORA HEART, INC Delivery devices and methods for heart valve repair
7753870, Mar 26 2004 Ethicon Endo-Surgery, Inc Systems and methods for treating obesity
7753924, Jul 27 2004 ANCORA HEART, INC Delivery devices and methods for heart valve repair
7753928, Apr 14 2005 Ethicon Endo-Surgery, Inc Method and device for use in minimally invasive placement of intragastric devices
7757924, Feb 05 2004 Ethicon Endo-Surgery, Inc Single fold system for tissue approximation and fixation
7758637, Jun 13 2002 ANCORA HEART, INC Delivery devices and methods for heart valve repair
7776059, Jun 28 2001 Suturing method
7789848, Oct 23 2002 Ethicon Endo-Surgery, Inc Method and device for use in endoscopic organ procedures
7862574, May 30 2001 Ethicon Endo-Surgery, Inc Obesity treatment tools and methods
7882995, Nov 30 2000 Boston Scientific Scimed, Inc. Stapling and cutting in resectioning for full thickness resection devices
7883538, Jun 13 2002 ANCORA HEART, INC Methods and devices for termination
7887564, Jan 25 2003 BOEHRINGER TECHNOLOGIES, L P Method for treating a wound
7892292, Aug 27 2001 Boston Scientific Scimed, Inc Positioning tools and methods for implanting medical devices
7896890, Sep 02 2005 Ethicon Endo-Surgery, Inc Method and apparatus for endoscopically performing gastric reduction surgery in a single step
7909219, Mar 18 2008 Boston Scientific Scimed, Inc Endoscopic stapling devices and methods
7909222, Mar 18 2008 Boston Scientific Scimed, Inc Endoscopic stapling devices and methods
7909223, Mar 18 2008 Boston Scientific Scimed, Inc Endoscopic stapling devices and methods
7909838, May 30 2001 Ethicon Endo-Surgery, Inc Obesity treatment tools and methods
7913892, Mar 18 2008 Boston Scientific Scimed, Inc Endoscopic stapling devices and methods
7914543, Oct 14 2003 Ethicon Endo-Surgery, Inc Single fold device for tissue fixation
7918845, Jan 15 2003 SOLAR CAPITAL LTD , AS SUCCESSOR AGENT Endoluminal tool deployment system
7918869, May 07 2004 SOLAR CAPITAL LTD , AS SUCCESSOR AGENT Methods and apparatus for performing endoluminal gastroplasty
7922062, Mar 18 2008 Boston Scientific Scimed, Inc Endoscopic stapling devices and methods
7922762, Sep 04 2003 ANCORA HEART, INC Devices and methods for cardiac annulus stabilization and treatment
7931661, Jun 14 2004 SOLAR CAPITAL LTD , AS SUCCESSOR AGENT Apparatus and methods for performing transluminal gastrointestinal procedures
7934631, Nov 10 2008 Boston Scientific Scimed, Inc Multi-fire stapling systems and methods for delivering arrays of staples
7942884, Dec 11 2002 SOLAR CAPITAL LTD , AS SUCCESSOR AGENT Methods for reduction of a gastric lumen
7942898, Dec 11 2002 SOLAR CAPITAL LTD , AS SUCCESSOR AGENT Delivery systems and methods for gastric reduction
7947055, Aug 30 2002 Ethicon Endo-Surgery, Inc Methods and devices for maintaining a space occupying device in a relatively fixed location within a stomach
7951157, May 19 2000 C.R. Bard, Inc. Tissue capturing and suturing device and method
7955340, Jun 25 1999 SOLAR CAPITAL LTD , AS SUCCESSOR AGENT Apparatus and methods for forming and securing gastrointestinal tissue folds
7981162, Aug 27 2001 Boston Scientific Scimed, Inc Satiation devices and methods
7993368, Mar 03 2000 C R BARD, INC Suture clips, delivery devices and methods
8007505, Oct 14 2003 Ethicon Endo-Surgery, Inc System for tissue approximation and fixation
8020741, Mar 18 2008 Boston Scientific Scimed, Inc Endoscopic stapling devices and methods
8021374, Mar 08 2005 The Trustees of Stevens Institute of Technology Method and device for the controlled delivery and placement of securing elements in a body
8029455, Jan 16 2003 Boston Scientific Scimed, Inc Satiation pouches and methods of use
8057384, Feb 27 2004 Ethicon Endo-Surgery, Inc Methods and devices for reducing hollow organ volume
8057386, Sep 06 2002 C.R. Bard, Inc. Integrated endoscope and accessory treatment device
8062207, Aug 07 2002 Ethicon Endo-Surgery, Inc Intra-gastric fastening devices
8066719, Dec 11 2002 SOLAR CAPITAL LTD , AS SUCCESSOR AGENT Apparatus and methods for forming gastrointestinal tissue approximations
8066766, Jun 13 2002 ANCORA HEART, INC Methods and devices for termination
8075573, May 16 2003 C R BARD, INC Single intubation, multi-stitch endoscopic suturing system
8075577, May 30 2001 Ethicon Endo-Surgery, Inc Obesity treatment tools and methods
8080022, May 30 2001 Ethicon Endo-Surgery, Inc Obesity treatment tools and methods
8080025, May 30 2001 Ethicon Endo-Surgery, Inc Obesity treatment tools and methods
8083756, Aug 30 2002 Ethicon Endo-Surgery, Inc Methods and devices for maintaining a space occupying device in a relatively fixed location within a stomach
8083757, Aug 30 2002 Ethicon Endo-Surgery, Inc Methods and devices for maintaining a space occupying device in a relatively fixed location within a stomach
8092378, Nov 17 2004 Ethicon Endo-Surgery, Inc Remote tissue retraction device
8092482, Aug 30 2002 Ethicon Endo-Surgery, Inc Stented anchoring of gastric space-occupying devices
8100822, Mar 16 2004 Covidien LP Anoscope for treating hemorrhoids without the trauma of cutting or the use of an endoscope
8100920, Mar 03 2000 C.R. Bard, Inc. Endoscopic tissue apposition device with multiple suction ports
8105351, May 19 2000 C R BARD, INC Method of promoting tissue adhesion
8109895, Sep 02 2006 Boston Scientific Scimed, Inc Intestinal sleeves and associated deployment systems and methods
8123765, May 30 2001 Ethicon Endo-Surgery, Inc Obesity treatment tools and methods
8137366, May 30 2001 Ethicon Endo-Surgery, Inc Obesity treatment tools and methods
8137367, May 30 2001 Ethicon Endo-Surgery, Inc Obesity treatment tools and methods
8147441, Oct 23 2002 Ethicon Endo-Surgery, Inc Method and device for use in endoscopic organ procedures
8206284, Sep 06 2002 C.R. Bard, Inc. Integrated endoscope and accessory treatment device
8206456, Oct 10 2003 Boston Scientific Scimed, Inc Restrictive and/or obstructive implant system for inducing weight loss
8216252, May 07 2004 SOLAR CAPITAL LTD , AS SUCCESSOR AGENT Tissue manipulation and securement system
8216253, May 07 2004 SOLAR CAPITAL LTD , AS SUCCESSOR AGENT Apparatus for manipulating and securing tissue
8216260, Dec 11 2002 SOLAR CAPITAL LTD , AS SUCCESSOR AGENT Apparatus and methods for forming and securing gastrointestinal tissue folds
8231641, Apr 16 2003 Ethicon Endo-Surgery, Inc Method and devices for modifying the function of a body organ
8236009, Sep 30 2004 SOLAR CAPITAL LTD , AS SUCCESSOR AGENT Needle assembly for tissue manipulation
8241202, Apr 26 2004 Boston Scientific Scimed, Inc Restrictive and/or obstructive implant for inducing weight loss
8252009, Mar 09 2004 Ethicon Endo-Surgery, Inc Devices and methods for placement of partitions within a hollow body organ
8257365, Feb 13 2004 Ethicon Endo-Surgery, Inc Methods and devices for reducing hollow organ volume
8257394, May 07 2004 SOLAR CAPITAL LTD , AS SUCCESSOR AGENT Apparatus and methods for positioning and securing anchors
8262676, Dec 11 2002 SOLAR CAPITAL LTD , AS SUCCESSOR AGENT Apparatus and methods for forming gastrointestinal tissue approximations
8277468, Jun 22 1999 Ethicon Endo-Surgery, Inc. Tissue reconfiguration
8287554, Jun 22 1999 Ethicon Endo-Surgery, Inc Method and devices for tissue reconfiguration
8287555, Jun 13 2002 ANCORA HEART, INC Devices and methods for heart valve repair
8287557, Jun 13 2002 ANCORA HEART, INC Methods and devices for termination
8298291, May 26 2005 SOLAR CAPITAL LTD , AS SUCCESSOR AGENT Methods and apparatus for securing and deploying tissue anchors
8337566, Apr 08 2002 Boston Scientific Scimed, Inc Method and apparatus for modifying the exit orifice of a satiation pouch
8343173, Jul 27 2004 ANCORA HEART, INC Delivery devices and methods for heart valve repair
8343175, Dec 12 2003 SOLAR CAPITAL LTD , AS SUCCESSOR AGENT Apparatus and methods for forming and securing gastrointestinal tissue folds
8353919, Jun 26 2003 LEE, Eui Tai Wound closure assisting and maintaining apparatus
8357174, Oct 14 2003 Single fold device for tissue fixation
8361086, Oct 21 1999 Edwards Lifesciences Corporation Minimally invasive mitral valve repair method and apparatus
8382775, Jan 08 2012 Vibrynt, Inc Methods, instruments and devices for extragastric reduction of stomach volume
8403838, Nov 17 2004 Ethicon Endo-Surgery, Inc Remote tissue retraction device
8403839, Nov 17 2004 Ethicon Endo-Surgery, Inc Remote tissue retraction device
8419755, May 30 2001 Ethicon Endo-Surgery, Inc Obesity treatment tools and methods
8430808, Mar 16 2004 Covidien LP Endoscopic method and device for avoiding cutting of rectal tissue in the treatment of hemorrhoids
8444657, May 07 2004 SOLAR CAPITAL LTD , AS SUCCESSOR AGENT Apparatus and methods for rapid deployment of tissue anchors
8448831, Nov 30 2000 Boston Scientific Scimed, Inc. Stapling and cutting in resectioning for full thickness resection devices
8449560, Mar 09 2004 Ethicon Endo-Surgery, Inc Devices and methods for placement of partitions within a hollow body organ
8454503, Nov 17 2004 Ethicon Endo-Surgery, Inc Remote tissue retraction device
8465504, Jan 25 2011 iSuturing, LLC Devices and methods for continuous surgical suturing
8469977, Oct 03 2005 Boston Scientific Scimed, Inc Endoscopic plication device and method
8486099, Jan 20 2010 Pavilion Medical Innovations, LLC; PAVILION MEDICAL INNOVATIONS Systems and methods for removal of intravascular leads
8500757, Jul 28 2009 Edwards Lifesciences Corporation Surgical puncture cinch and closure system
8506479, Dec 16 2009 LUMENR, LLC ; Boston Scientific Scimed, Inc Substantially rigid and stable endoluminal surgical suite for treating a gastrointestinal lesion
8568488, Aug 27 2001 Boston Scientific Scimed, Inc Satiation devices and methods
8573226, Jun 14 2004 SOLAR CAPITAL LTD , AS SUCCESSOR AGENT Apparatus and methods for performing transluminal gastrointestinal procedures
8574243, Jun 25 1999 SOLAR CAPITAL LTD , AS SUCCESSOR AGENT Apparatus and methods for forming and securing gastrointestinal tissue folds
8585724, Jan 25 2011 Gyrus Ent, L.L.C.; GYRUS ENT, L L C Surgical cutting instrument with distal suction capability
8590761, Feb 05 2004 Ethicon Endo-Surgery, Inc Single fold system for tissue approximation and fixation
8613749, May 30 2001 Ethicon Endo-Surgery, Inc Obesity treatment tools and methods
8628547, Mar 09 2004 Ethicon Endo-Surgery, Inc Devices and methods for placement of partitions within a hollow body organ
8632458, Oct 26 2011 Covidien LP Gentle hemorrhoid treatment offering a substantially painless healing
8632558, Jan 20 2010 PAVILION MEDICAL INNOVATIONS Systems and methods for removal of intravascular leads
8641727, Jun 13 2002 ANCORA HEART, INC Devices and methods for heart valve repair
8641729, Jul 13 2005 Creighton University Systems and techniques for minimally invasive gastrointestinal procedures
8679134, Aug 08 2007 SPIRX PTE LTD Methods and devices for delivering sutures in tissue
8715166, Mar 16 2004 Covidien LP Gentle method of treating a hemorrhoid
8726909, Jan 27 2006 SOLAR CAPITAL LTD , AS SUCCESSOR AGENT Methods and apparatus for revision of obesity procedures
8747421, Nov 10 2008 Boston Scientific Scimed, Inc Multi-fire stapling systems and methods for delivering arrays of staples
8784306, Nov 17 2004 Ethicon Endo-Surgery, Inc Remote tissue retraction device
8784354, Aug 27 2001 Boston Scientific Scimed, Inc Positioning tools and methods for implanting medical devices
8784500, Oct 10 2003 Boston Scientific Scimed, Inc Devices and methods for retaining a gastro-esophageal implant
8790367, Feb 06 2008 ANCORA HEART, INC Multi-window guide tunnel
8794243, Mar 27 2003 Ethicon Endo-Surgery, Inc. Obesity treatment tools and methods
8795166, Nov 17 2004 Ethicon Endo-Surgery, Inc Remote tissue retraction device
8795298, Oct 10 2008 ANCORA HEART, INC Tether tensioning devices and related methods
8801650, Oct 23 2002 Ethicon Endo-Surgery, Inc. Method and device for use in endoscopic organ procedures
8828025, Feb 13 2004 Ethicon Endo-Surgery, Inc Methods and devices for reducing hollow organ volume
8828027, May 07 2004 SOLAR CAPITAL LTD , AS SUCCESSOR AGENT Tissue manipulation and securement system
8845753, Aug 27 2001 Boston Scientific Scimed, Inc. Satiation devices and methods
8852216, Mar 23 2007 Ethicon Endo-Surgery, Inc Tissue approximation methods
8863748, Jul 31 2008 Olympus Corporation Endoscopic surgical operation method
8864008, Mar 18 2008 Boston Scientific Scimed, Inc Endoscopic stapling devices and methods
8870916, Jul 07 2006 SOLAR CAPITAL LTD , AS SUCCESSOR AGENT Low profile tissue anchors, tissue anchor systems, and methods for their delivery and use
8882785, Sep 29 2008 C R BARD, INC Endoscopic suturing device
8906039, Mar 21 2005 Design Standards Corporation Suturing device
8906040, Jul 13 2005 Creighton University Systems and techniques for minimally invasive gastrointestinal procedures
8906052, May 08 2009 University of South Florida Method and device for the treatment of hypertrophic cardiomyopathy
8926634, May 07 2004 SOLAR CAPITAL LTD , AS SUCCESSOR AGENT Apparatus and methods for manipulating and securing tissue
8932211, Jun 22 2012 LUMENR LLC ; Boston Scientific Scimed, Inc Floating, multi-lumen-catheter retractor system for a minimally-invasive, operative gastrointestinal treatment
8939902, Nov 17 2004 Ethicon Endo-Surgery, Inc. Remote tissue retraction device
8945167, Dec 31 2007 Boston Scientific Scimed, Inc Gastric space occupier systems and methods of use
8961539, May 04 2009 Boston Scientific Scimed, Inc Endoscopic implant system and method
8968275, Apr 26 2010 Covidien LP Apparatus and method for effecting at least one anatomical structure
8992457, Aug 27 2001 Boston Scientific Scimed, Inc Gastrointestinal implants
8992570, Mar 03 2000 C.R. Bard, Inc. Suture clips, delivery devices and methods
9005220, Apr 04 2006 C R BARD, INC Suturing devices and methods with energy emitting elements
9011317, Apr 26 2010 Covidien LP Gentle hemorrhoid treatment offering a substantially painless healing
9028511, Mar 09 2004 Ethicon Endo-Surgery, Inc Devices and methods for placement of partitions within a hollow body organ
9039601, Mar 16 2004 LUMENR, LLC ; Boston Scientific Scimed, Inc Endoluminal treatment method and associated surgical assembly including tissue occlusion device
9044267, Jun 11 2010 ENTOURAGE MEDICAL TECHNOLOGIES, INC. System and method for transapical access and closure
9055942, Oct 03 2005 Boston Scientific Scimed, Inc Endoscopic plication devices and methods
9072513, Jun 13 2002 ANCORA HEART, INC Methods and devices for termination
9078633, Mar 14 2009 VASOSTITCH, INC Vessel access and closure device
9107727, Aug 27 2001 Satiation devices and methods
9119622, May 03 2006 Indiana University Research & Technology Corporation Methods and apparatuses for reshaping the esophagus and other body lumens
9125636, Dec 16 2009 LUMENR; Boston Scientific Scimed, Inc Endoluminal device with retractor system
9138340, Aug 27 2001 Boston Scientific Scimed, Inc. Gastro-esophageal implants
9155528, Jan 08 2012 Vibrynt, Inc. Methods, instruments and devices for extragastic reduction of stomach volume
9161746, Dec 16 2009 LUMENR, LLC ; Boston Scientific Scimed, Inc Substaintially rigid and stable endoluminal surgical suite for treating a gastrointestinal lesion
9161778, Jun 11 2010 ENTOURAGE MEDICAL TECHNOLOGIES, INC. System and method for transapical access and closure
9180035, Oct 10 2003 Boston Scientific Scimed, Inc Devices and methods for retaining a gastro-esophageal implant
9180036, Aug 27 2001 Boston Scientific Scimed, Inc. Methods for implanting medical devices
9186130, Dec 16 2009 LUMENR, LLC ; Boston Scientific Scimed, Inc Endoluminal system for gastrointestinal treatment
9186131, Dec 16 2009 LUMENR, LLC ; Boston Scientific Scimed, Inc Multi-lumen-catheter retractor system for a minimally-invasive, operative gastrointestinal treatment
9186176, Jun 11 2010 ENTOURAGE MEDICAL TECHNOLOGIES, INC. System and method for transapical access and closure
9186268, Oct 14 2003 Ethicon Endo-Surgery, Inc. Single fold device for tissue fixation
9220498, Jan 25 2011 iSuturing, LLC Methods and sutures for continuous surgical suturing
9226825, Jun 13 2002 ANCORA HEART, INC Delivery devices and methods for heart valve repair
9248038, Oct 10 2003 Boston Scientific Scimed, Inc. Methods for retaining a gastro-esophageal implant
9254214, Aug 27 2001 Boston Scientific Scimed, Inc Satiation devices and methods
9265514, Apr 17 2012 A-BASE KORLATOLT FELELOSSEGU TARSASAG Manipulator for grasping tissue
9277915, Jun 26 2010 VASOSTITCH, INC Method and apparatus for transapical access and closure
9307981, Dec 28 2006 Olympus Corporation Method for suturing a gastric wall
9314361, Sep 15 2006 Boston Scientific Scimed, Inc System and method for anchoring stomach implant
9314362, Jan 08 2012 Vibrynt, Inc Methods, instruments and devices for extragastric reduction of stomach volume
9358144, Aug 27 2001 Boston Scientific Scimed, Inc. Gastrointestinal implants
9398910, Sep 20 2010 ENTOURAGE MEDICAL TECHNOLOGIES, INC Method for providing surgical access
9445791, Oct 10 2003 Boston Scientific Scimed, Inc Systems and methods related to gastro-esophageal implants
9451956, Nov 10 2008 Boston Scientific Scimed, Inc Multi-fire stapling systems
9456825, Jul 18 2007 Boston Scientific Scimed, Inc Endoscopic implant system and method
9468434, Jun 03 2014 Covidien LP Stitching end effector
9468528, Jun 13 2002 ANCORA HEART, INC Devices and methods for heart valve repair
9492653, Jan 20 2010 Pavilion Medical Innovations, LLC Systems and methods for removal of intravascular leads
9498244, Oct 19 2012 Minerva Surgical, Inc Medical systems and methods
9510817, May 07 2004 SOLAR CAPITAL LTD , AS SUCCESSOR AGENT Apparatus for manipulating and securing tissue
9545249, Jul 18 2007 Boston Scientific Scimed, Inc. Overtube introducer for use in endoscopic bariatric surgery
9554690, Dec 16 2009 LUMENR, LLC ; Boston Scientific Scimed, Inc Endoluminal device with retractor system
9565998, Dec 16 2009 LUMENR, LLC ; Boston Scientific Scimed, Inc Multi-lumen-catheter retractor system for a minimally-invasive, operative gastrointestinal treatment
9579097, Sep 20 2010 ENTOURAGE MEDICAL TECHNOLOGIES, INC Method for tensioning a surgical closure
9585651, May 26 2005 SOLAR CAPITAL LTD , AS SUCCESSOR AGENT Methods and apparatus for securing and deploying tissue anchors
9610088, Apr 17 2012 A-BASE KORLATOLT FELELOSSEGU TARSASAG Manipulator for grasping tissue
9616197, Jan 20 2009 ANCORA HEART, INC Anchor deployment devices and related methods
9622774, Jun 11 2010 ENTOURAGE MEDICAL TECHNOLOGIES, INC. System and method for transapical access and closure
9629651, May 08 2009 University of South Florida Device for the treatment of hypertrophic cardiomyopathy
9636106, Oct 10 2008 ANCORA HEART, INC Termination devices and related methods
9636107, Jun 13 2002 ANCORA HEART, INC Devices and methods for heart valve repair
9636114, Mar 18 2008 Boston Scientific Scimed, Inc Endoscopic stapling devices
9655506, Dec 16 2009 Boston Scientific Scimed, Inc; LUMENR, LLC Endoluminal device with retractor system
9661984, Mar 16 2004 LUMENR, LLC ; Boston Scientific Scimed, Inc Endoluminal treatment method and associated surgical assembly
9675338, Sep 20 2010 ENTOURAGE MEDICAL TECHNOLOGIES, INC System for providing surgical access
9687334, Sep 02 2006 Boston Scientific Scimed, Inc Intestinal sleeves and associated deployment systems and methods
9706996, Feb 06 2008 ANCORA HEART, INC Multi-window guide tunnel
9713416, Dec 16 2009 LUMENR, LLC ; Boston Scientific Scimed, Inc Endoluminal system and method for gastrointestinal treatment
9717494, Dec 13 2011 Ethicon Endo-Surgery, Inc Applier for anchoring a lining to a hollow organ
9730687, Oct 29 2013 ENTOURAGE MEDICAL TECHNOLOGIES, INC System for providing surgical access
9730690, Sep 20 2010 ENTOURAGE MEDICAL TECHNOLOGIES, INC Method for providing surgical access
9737194, Dec 16 2009 LUMENR, LLC ; Boston Scientific Scimed, Inc Endoluminal system for gastrointestinal treatment
9770239, Jan 25 2011 iSuturing, LLC Suture stitches for continuous surgical suturing
9775602, Jan 25 2011 iSuturing, LLC Devices and methods for continuous surgical suturing
9782168, Sep 20 2010 ENTOURAGE MEDICAL TECHNOLOGIES, INC System for providing surgical access
9788984, Aug 27 2001 Boston Scientific Scimed, Inc. Satiation devices and methods
9833250, Apr 26 2010 Covidien LP Apparatus and method for effecting at least one anatomical structure
9844453, Aug 27 2001 Boston Scientific Scimed, Inc. Positioning tools and methods for implanting medical devices
9861350, Sep 03 2010 ANCORA HEART, INC Devices and methods for anchoring tissue
9867633, Mar 16 2004 Covidien LP Endoluminal treatment method and associated surgical assembly including tissue occlusion device
9872786, Aug 27 2001 Boston Scientific Scimed, Inc. Gastro-esophageal implants
9883857, Oct 29 2013 ENTOURAGE MEDICAL TECHNOLOGIES, INC System for providing surgical access
9883879, Apr 26 2010 Covidien LP Apparatus for treating hemorrhoids
9901337, Jan 25 2011 iSuturing, LLC Suture stitches for continuous surgical suturing
9949631, Apr 26 2010 Covidien LP Gentle hemorrhoid treatment offering a substantially painless healing
9949829, Jun 13 2002 ANCORA HEART, INC Delivery devices and methods for heart valve repair
9999422, May 27 2010 HOWMEDICA OSTEONICS CORP Apparatus and methods for achilles tendon repair
ER4197,
RE48485, Dec 16 2009 Boston Scientific Scimed, Inc. Endoluminal device with retractor system
RE48597, Dec 16 2009 Boston Scientific Scimed, Inc. Endoluminal system and method for gastrointestinal treatment
RE48684, Dec 16 2009 Boston Scientific Scimed, Inc. Endoluminal device with retractor system
RE48729, Dec 16 2009 Boston Scientific Scimed, Inc. Endoluminal system for gastrointestinal treatment
RE48750, Dec 16 2009 Boston Scientific Scimed, Inc. Substaintially rigid and stable endoluminal surgical suite for treating a gastrointestinal lesion
RE48800, Dec 16 2009 Boston Scientific Scimed, Inc. Endoluminal system for gastrointestinal treatment
RE48850, Dec 16 2009 Boston Scientific Scimed, Inc. Multi-lumen-catheter retractor system for a minimally-invasive, operative gastrointestinal treatment
Patent Priority Assignee Title
4557265, Feb 08 1983 Innova AB Suturing instrument
4598710, Jan 20 1984 URBAN ENGINEERING COMPANY, INC , A CORP OF CALIFORNIA Surgical instrument and method of making same
4603694, Mar 08 1983 SMITH & NEPHEW RICHARDS, INC Arthroscopic shaver
4662869, Nov 19 1984 Precision intraocular apparatus
4683885, Apr 12 1984 Richard Wolf GmbH Method for tying sewing threads
5226910, Jul 05 1989 Kabushiki Kaisha Topcon Surgical cutter
5269791, Oct 09 1992 Surgical knot pushing appliance
5284472, Oct 30 1992 Abbott Medical Optics Inc Vitreous cutter
5292327, Oct 08 1992 Surgical knot pusher
5336229, Feb 09 1993 IMAGYN MEDICAL TECHNOLOGIES, INC Dual ligating and dividing apparatus
5395313, Aug 13 1993 Reciprocating arthroscopic shaver
5409013, Nov 06 1989 Mectra Labs, Inc. Tissue removal assembly
5441510, Sep 01 1993 Advanced Cardiovascular Systems, INC Bi-axial cutter apparatus for catheter
5458112, Aug 15 1994 Kimberly-Clark Worldwide, Inc Biliary biopsy device
5505210, Nov 06 1989 Mectra Labs, Inc. Lavage with tissue cutting cannula
5527322, Nov 08 1993 Abbott Laboratories Device and method for suturing of internal puncture sites
5562685, Sep 16 1994 General Surgical Innovations, Inc. Surgical instrument for placing suture or fasteners
5569277, Sep 12 1989 Advanced Cardiovascular Systems, INC Atherectomy device having helical blade and blade guide
5582616, Aug 05 1994 Tyco Healthcare Group LP Surgical helical fastener with applicator
5643304, Oct 06 1994 Hologic, Inc; Biolucent, LLC; Cytyc Corporation; CYTYC SURGICAL PRODUCTS, LIMITED PARTNERSHIP; SUROS SURGICAL SYSTEMS, INC ; Third Wave Technologies, INC; Gen-Probe Incorporated Method and apparatus for minimally invasive tissue removal
DE2453058,
DE2848314,
DE4120329,
DEO9428801,
EP541377A1,
GB2038640,
RE33258, Nov 30 1987 HOWMEDICA OSTEONICS CORP Irrigating, cutting and aspirating system for percutaneous surgery
SU1454457,
WO9314700,
WO9416181,
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Mar 16 1998Boston Scientific Corporation(assignment on the face of the patent)
May 18 1998SOLAR, MATTHEW S Boston Scientific CorpASSIGNMENT OF ASSIGNORS INTEREST SEE DOCUMENT FOR DETAILS 0092530070 pdf
May 18 1998KRATSCH, PETER K Boston Scientific CorpASSIGNMENT OF ASSIGNORS INTEREST SEE DOCUMENT FOR DETAILS 0092530070 pdf
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Jul 14 1998KRATSCH, PETER K Boston Scientific CorporationASSIGNMENT OF ASSIGNORS INTEREST SEE DOCUMENT FOR DETAILS 0093460417 pdf
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