The ornamental design for a sprayer with a hand operated pump and bottle, as shown and described.
FIG. 1 is a top rear and left perspective view of the sprayer with a hand operated pump and bottle showing my new design;
FIG. 2 is a left side elevational view thereof;
FIG. 3 is a front elevational view thereof;
FIG. 4 is a rear elevational view thereof;
FIG. 5 is a top view thereof;
FIG. 6 is a bottom view thereof, the broken lines are included for the purpose of illustrating the portions of the sprayer with a hand pump and bottle that form no part of the claimed design; and,