A method for using a synchrotron, the method including the steps of: providing a synchrotron designed to accelerate a hadron beam to higher momenta; altering said synchrotron to enable deceleration of hadron beams to lower momenta; and using the synchrotron in said altering step in decelerating a hadron beam to lower momentum.

Patent
   RE46383
Priority
Aug 30 2001
Filed
Nov 20 2006
Issued
May 02 2017
Expiry
Aug 29 2022
Assg.orig
Entity
unknown
0
32
EXPIRED
0. 56. A method for using a synchrotron, the method comprising:
using the synchrotron to decelerate an antiproton beam to lower momentum;
extracting the decelerated antiproton beam from the synchrotron; and
delivering the extracted antiproton beam into living tissue.
1. A method for using a synchrotron, the method comprising the steps of: providing altering a synchrotron designed to accelerate a hadron beam from initial momentum to higher momenta; altering said synchrotron momentum to enable deceleration of the hadron beams beam to lower momenta momentum than said initial momentum by using a radio-frequency acceleration system to impose momentum reduction on the hadron beam; and using the altered synchrotron in said altering step in decelerating the hadron beam to lower momenta.
0. 63. A method for treating a patient, the method comprising:
creating an antiproton beam at an energy higher than a predetermined irradiation energy level;
decelerating said antiproton beam to the predetermined irradiation energy level, said decelerating using a radio-frequency acceleration system to impose momentum reduction;
exposing at least a portion of the patient body to said antiprotons at the predetermined irradiation energy level;
generating radioisotopes within said body by said exposing; and
providing patient therapy with said radioisotopes.
0. 64. A method for imaging a patient, the method comprising:
creating an antiproton beam at an energy higher than a predetermined irradiation energy level;
decelerating said antiproton beam to the predetermined irradiation energy level, said decelerating using a radio-frequency acceleration system to impose momentum reduction;
exposing at least a portion of the patient body to said antiproton beam at the predetermined irradiation energy level;
generating radioisotopes within said body by said exposing; and
providing patient imaging with said radioisotopes.
0. 61. A method for treating a patient having a plurality of undesirable cells, the method comprising:
creating an antiproton beam at an energy higher than a predetermined therapeutic energy level;
decelerating said antiproton beam to a predetermined, therapeutic energy level, said decelerating using a radio-frequency acceleration system to impose momentum reduction;
exposing at least a portion of the plurality of undesirable cells to said beam;
generating radioisotopes within the plurality of undesirable cells by said exposing; and
monitoring the decay radiation from said radioisotopes.
2. The method of claim 1, wherein the step of altering includes modifying a dipole power supply system of the synchrotron to maintain a bending magnetic field during the decelerating of the hadron beam.
3. The method of claim 1, wherein the step of altering includes modifying a quadruple power supply system of the synchrotron to maintain focusing and defocusing magnetic fields during the decelerating of the hadron beam.
4. The method of claim 1, wherein the step of altering includes modifying a sextuple power supply system of the synchrotron to maintain chromaticity control during the decelerating of the hadron beam.
5. The method of claim 1, wherein the step of altering includes modifying a dipole corrector power supply system of the synchrotron to maintain a trajectory correction magnetic field during the decelerating of the hadron beam.
6. The method of claim 1, wherein the step of altering includes modifying a radio frequency acceleration system of the synchrotron to impose phase stable momentum reduction during the decelerating of the hadron beam.
7. The method of claim 1, wherein the step of altering includes modifying a computer control system of the synchrotron to enable the decelerating of the hadron beam.
8. The method of claim 1, wherein the step of decelerating is carried out with said hadron beam including protons.
9. The method of claim 1, wherein the step of decelerating is carried out with said hadron beam including antiprotons.
10. The method of claim 1, wherein the step of decelerating is carried out with said hadron beam including atomic ions.
11. The method of claim 2, wherein the step of modifying includes adding a dipole power supply component to ensure that electrical current from the dipole power supply system follows commands from a computer control system.
12. The method of claim 2, wherein the step of modifying includes removing a dipole power supply component to ensure that electrical current from the dipole power supply system follows commands from a computer control system.
13. The method of claim 2, wherein the step of modifying includes altering a dipole power supply component to ensure that electrical current from the dipole power supply system follows commands from a computer control system.
14. The method of claim 2, wherein the step of modifying includes adding a computer control system component to direct the dipole power supply system to follow the commands from said computer control system.
15. The method of claim 2, wherein the step of modifying includes removing a computer control system component to direct the dipole power supply system to follow commands from said computer control system.
16. The method of claim 2, wherein the step of modifying includes altering a computer control system component to direct the dipole power supply system to follow commands from said computer control system.
17. The method of claim 2, wherein the step of modifying includes altering a value of a computer control system database variable to direct the dipole power supply system to follow commands from said computer control system.
18. The method of claim 2, wherein the step of modifying includes altering a byte of information stored in a computer control system component to direct the dipole power supply system to follow commands from said computer control system.
19. The method of claim 2, wherein the step of modifying includes altering a value of a computer control system variable to direct the dipole power supply system to follow commands from said computer control system.
20. The method of claim 3, wherein step of modifying includes adding a quadruple power supply component to ensure that electrical current from the quadruple power supply system follows commands from a computer control system.
21. The method of claim 3, wherein the step of modifying includes removing a quadruple power supply component to ensure that electrical current from the quadruple power supply system follows commands from a computer control system.
22. The method of claim 3, wherein the step of modifying includes altering a quadruple power supply component to ensure that electrical current from the power supply follows commands from a computer control system.
23. The method of claim 3, wherein the step of modifying includes adding a computer control system component to direct the quadruple power supply system to follow the commands from said computer control system.
24. The method of claim 3, wherein the step of modifying includes removing a computer control system component to direct the quadruple power supply system to follow commands from said computer control system.
25. The method of claim 3, wherein the step of modifying includes altering a computer control system component to direct the quadruple power supply system to follow commands from said computer control system.
26. The method of claim 3, wherein the step of modifying includes altering a value of a computer control system database variable to direct the quadruple power supply system to follow commands from said computer control system.
27. The method of claim 3, wherein the step of modifying includes altering a byte of information stored in a computer control system component to direct the quadruple power supply system to follow commands from said computer control system.
28. The method of claim 3, wherein the step of modifying includes altering a value of a computer control system variable to direct the quadruple power supply system to follow commands from said computer control system.
29. The method of claim 4, wherein step of modifying includes adding a sextuple power supply component to ensure that electrical current from the sextuple power supply system follows commands from a computer control system.
30. The method of claim 4, wherein the step of modifying includes removing a sextuple power supply component to ensure that electrical current from the sextuple power supply system follows commands from a computer control system.
31. The method of claim 4, wherein the step of modifying includes altering a sextuple power supply component to ensure that electrical current from the sextuple power supply system follows commands from a computer control system.
32. The method of claim 4, wherein the step of modifying includes adding a computer control system component to direct the sextuple power supply system to follow the commands from said computer control system.
33. The method of claim 4, wherein the step of modifying includes removing a computer control system component to direct the sextuple power supply system to follow commands from said computer control system.
34. The method of claim 4, wherein the step of modifying includes altering a computer control system component to direct the sextuple power supply system to follow commands from said computer control system.
35. The method of claim 4, wherein the step of modifying includes altering a value of a computer control system database variable to direct the sextuple power supply system to follow commands from said computer control system.
36. The method of claim 4, wherein the step of modifying includes altering a byte of information stored in a computer control system component to direct the sextuple power supply system to follow commands from said computer control system.
37. The method of claim 4, wherein the step of modifying includes altering a value of a computer control system variable to direct the sextuple power supply system to follow commands from said computer control system.
38. The method of claim 5, wherein step of modifying includes adding a dipole corrector power supply component to ensure that electrical current from the dipole corrector power supply system follows commands from a computer control system.
39. The method of claim 5, wherein the step of modifying includes removing a dipole corrector power supply component to ensure that electrical current from the dipole corrector power supply system follows commands from a computer control system.
40. The method of claim 5, wherein the step of modifying includes altering a dipole corrector power supply component to ensure that electrical current from the dipole corrector power supply system follows commands from a computer control system.
41. The method of claim 5, wherein the step of modifying includes adding a computer control system component to direct the dipole corrector power supply system to follow the commands from said computer control system.
42. The method of claim 5, wherein the step of modifying includes removing a computer control system component to direct the dipole corrector power supply system to follow commands from said computer control system.
43. The method of claim 5, wherein the step of modifying includes altering a computer control system component to direct the dipole corrector power supply system to follow commands from said computer control system.
44. The method of claim 5, wherein the step of modifying includes altering a value of a computer control system database variable to direct the dipole corrector power supply system to follow commands from said computer control system.
45. The method of claim 5, wherein the step of modifying includes altering a byte of information stored in a computer control system component to direct the dipole corrector power supply system to follow commands from said computer control system.
46. The method of claim 5, wherein the step of modifying includes altering a value of a computer control system variable to direct the dipole corrector power supply system to follow commands from said computer control system.
47. The method of claim 6, wherein step of modifying includes adding a radio frequency acceleration system component to ensure that an electromagnetic field of said radio frequency acceleration system follows commands from a computer control system.
48. The method of claim 6, wherein the step of modifying includes removing a radio frequency acceleration system component to ensure that an electromagnetic field of said radio frequency acceleration system follows commands from a computer control system.
49. The method of claim 6, wherein the step of modifying includes altering a radio frequency acceleration system component to ensure that an electromagnetic field of said radio frequency acceleration system follows commands from a computer control system.
50. The method of claim 6, wherein the step of modifying includes adding a computer control system component to direct the radio frequency acceleration system to follow the commands from said computer control system.
51. The method of claim 6, wherein the step of modifying includes removing a computer control system component to direct the radio frequency acceleration system to follow commands from said computer control system.
52. The method of claim 6, wherein the step of modifying includes altering a computer control system component to direct the radio frequency acceleration system to follow commands from said computer control system.
53. The method of claim 6, wherein the step of modifying includes altering a value of a computer control system database variable to direct the radio frequency acceleration system to follow commands from said computer control system.
54. The method of claim 6, wherein the step of modifying includes alerting a byte of information stored in a computer control system component to direct the radio frequency acceleration system to follow commands from said computer control system.
55. The method of claim 6, wherein the step of modifying includes altering a value of a computer control system variable to direct the radio frequency acceleration system to follow commands from said computer control system.
0. 57. The method of claim 56, wherein the living tissue comprises cancerous cells.
0. 58. The method of claim 56, wherein nuclei in the living tissue is partially transmuted via antiproton annihilations into radioisotopes.
0. 59. The method of claim 58, wherein the radioisotopes are used in imaging techniques.
0. 60. The method of claim 58, wherein the radioisotopes are used for therapeutic treatment.
0. 62. The method of claim 61, wherein the cells are cancerous.
0. 65. The method of claim 1, wherein the hadron beam at the lower momenta comprises a decelerated antiproton beam, and further including:
extracting the decelerated antiproton beam from the synchrotron; and
delivering the extracted antiproton beam into living tissue.
0. 66. The method of claim 1, wherein the step of using the synchrotron includes creating an antiproton beam at an energy higher than a predetermined therapeutic energy level, and the step of decelerating includes decelerating said antiprotons to a predetermined, therapeutic energy level; and further comprising:
exposing at least a portion of a plurality of undesirable cells to said beam of antiprotons;
generating radioisotopes within the plurality of undesirable cells by said exposing; and
monitoring the decay radiation from said radioisotopes.
0. 67. The method of claim 1, wherein the step of using the synchrotron includes creating an antiproton beam at an energy higher than a predetermined irradiation energy level, and the decelerating includes decelerating said antiproton beam to the predetermined, irradiation energy level; and further comprising:
exposing at least a portion of the patient body to said antiproton beam at the predetermined irradiation energy level;
generating radioisotopes within said body by said exposing; and
providing patient imaging with said radioisotopes.

FIG. 10, which is incorporated by reference from Ser. No. 60/316,711 filed Aug. 30, 2001, is a dose vs. depth curve for antiproton radiation, x-ray radiation, and proton radiation.FIG. 14 shows ionization tracks for protons in water and heavy ions in water, at a tumor, slowing hear the tumor, and entering the body. FIG. 14 also shows increased lethality to cancer cells and decreased collateral damage.


where

The smallest opening angle we should expect is 16 degrees (5 cm separation at 15 cm from annihilation site). However, the average opening angle will be around 40 degrees (9 cm separation at 15 cm from the annihilation site). The PbWO4 would loose some efficiency in separating the decay gammas as compared to the tungsten shower detector at the higher pion momenta.

It should be clear that a shower detector would be quite massive (>400 lbs for steradians).

Two techniques for localizing the proton-antiproton annihilation site have been examined for the case where the site is at the center of a 30 cm diameter sphere of water. Tracking charged pions beyond the sphere is limited to >1.5 mm precision on the vertex reconstruction due to multiple scattering in traversing the 15 cm of water. Pointing of the shower axis from neutral pion decays is expected to yield a vertex localization precision of <0.5 mm. The shower detection can be done using fast scintillator <<15 ns) allowing a faster response than the charged particle tracking.

Jackson, Gerald Peter

Patent Priority Assignee Title
Patent Priority Assignee Title
4491948, Feb 13 1981 Isochronous free electron laser
4657722, Jan 24 1980 Ion cluster acceleration
4780683, Jun 05 1986 Mitsubishi Denki Kabushiki Kaisha Synchrotron apparatus
5001437, Jun 29 1988 Hitachi, Ltd. Electron storage ring
5051600, Aug 17 1990 TYCO ELECTRONICS CORPORATION, A CORPORATION OF PENNSYLVANIA Particle beam generator
5073913, Apr 26 1988 ACCTEK Associates, Inc. Apparatus for acceleration and application of negative ions and electrons
5138271, Feb 23 1989 Method for cooling a charged particle beam
5339812, Mar 28 1990 Medical Instrumentation and Diagnostic Corporation; Tyrone L., Hardy Three-dimensional computer graphics simulation and computerized numerical optimization for dose delivery and treatment planning
5363008, Oct 08 1991 Hitachi, Ltd. Circular accelerator and method and apparatus for extracting charged-particle beam in circular accelerator
5374913, Dec 13 1991 Houston Advanced Research Center Twin-bore flux pipe dipole magnet
5538494, Mar 17 1994 Hitachi, Ltd. Radioactive beam irradiation method and apparatus taking movement of the irradiation area into consideration
5557178, Nov 01 1994 Cornell Research Foundation, Inc. Circular particle accelerator with mobius twist
5600213, Jul 20 1990 Hitachi, Ltd. Circular accelerator, method of injection of charged particles thereof, and apparatus for injection of charged particles thereof
5698954, Sep 20 1993 Hitachi, Ltd. Automatically operated accelerator using obtained operating patterns
5789875, Jul 20 1990 Hitachi, Ltd. Circular accelerator, method of injection of charged particle thereof, and apparatus for injection of charged particle thereof
5895926, Feb 15 1995 Loma Linda University Medical Center Beamline control and security system for a radiation treatment facility
5969367, Aug 30 1996 Hitachi, LTD Charged particle beam apparatus and method for operating the same
5977554, Mar 23 1998 NANOLIFE HOLDINGS, LLC; NANO-LIFE HOLDINGS, LLC Container for transporting antiprotons
6160263, Mar 23 1998 NANOLIFE HOLDINGS, LLC; NANO-LIFE HOLDINGS, LLC Container for transporting antiprotons
6198957, Dec 19 1997 Varian Medical Systems, Inc Radiotherapy machine including magnetic resonance imaging system
6265837, Mar 10 1998 Hitachi, Ltd. Charged-particle beam irradiation method and system
6316776, Aug 30 1996 Hitachi, LTD Charged particle beam apparatus and method for operating the same
6414331, Mar 23 1998 NANOLIFE HOLDINGS, LLC; NANO-LIFE HOLDINGS, LLC Container for transporting antiprotons and reaction trap
6433349, Mar 10 1998 Hitachi, Ltd. Charged-particle beam irradiation method and system
6462490, Jul 29 1999 Hitachi, LTD; HITACHI INFORMATION & CONTROL SYSTEMS, INC Method and apparatus for controlling circular accelerator
6576916, Mar 23 1998 NANOLIFE HOLDINGS, LLC; NANO-LIFE HOLDINGS, LLC Container for transporting antiprotons and reaction trap
6606370, Jul 19 1999 System for the storage and transportation of anti-matter
6815688, Jan 09 2002 Biomed Solutions LLC Devices for guiding and manipulating electron beams
6826423, Jan 04 1999 Medical Instrumentation and Diagnostics Corporation Whole body stereotactic localization and immobilization system
20030183783,
20040096033,
20040162457,
//
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Feb 01 2008JACKSON, GERALD PETERHBar Technologies, LLCASSIGNMENT OF ASSIGNORS INTEREST SEE DOCUMENT FOR DETAILS 0205840669 pdf
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