A scanning system having a plurality of x-ray sources together with a single x-ray detector that uses sequentially emitted overlapping fan-shaped or cone-shaped beams to image a target such as the leg of a horse. The x-ray detector is rotated closer to the target and the x-ray emitter sources are rotated at a greater distance from the target. The positioning systems of the x-ray detector and the x-ray sources may be operated independently of one another, with each of the x-ray detector and the x-ray sources being also rotated about separate axes passing therethrough (while they are both being rotated around the target) as a way to keep the x-ray sources and the x-ray detector parallel to one another while working in very tight spaces.
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1. A scanning system, comprising:
an x-ray detector;
a plurality of x-ray sources positioned in a spherical orientation with respect to the x-ray detector;
a positioning system for rotating the x-ray detector in a first radius around the target; and
a positioning system for rotating the plurality of x-ray sources in a second radius around the target;
wherein the first radius is smaller than the second radius.
20. A method of scanning a target, comprising:
providing a plurality of x-ray sources on a first support;
providing an x-ray detector on a second support; and
imaging a target by rotating the plurality of x-ray sources around an axis and rotating the x-ray detector around another axis while simultaneously rotating the plurality of x-ray sources and the x-ray detector around the target, while
sequentially emitting overlapping beams from the plurality of x-ray sources onto the x-ray detector.
14. A scanning system comprising:
a plurality of x-ray sources that each emits a cone-shaped beam;
an x-ray detector that is a planar detector;
a positioning system for rotating the x-ray detector in a first radius around the target; and
a positioning system for rotating the plurality of x-ray sources in a second radius around the target, the first radius being smaller than the second radius;
wherein the positioning system for rotating the x-ray detector both rotates the x-ray detector around the target, and rotates the x-ray detector about an axis, and
wherein the positioning system for rotating the x-ray sources both rotates the x-ray sources around the target, and rotates the x-ray sources about an axis.
2. The scanning system of
3. The scanning system of
4. The scanning system of
5. The scanning system of
6. The scanning system of
7. The scanning system of
a control system for sequentially activating the x-ray sources.
8. The scanning system of
9. The scanning system of
a longitudinal positioning system for simultaneously moving the x-ray sources and the x-ray detector longitudinally along the length of the target.
10. The scanning system of
11. The scanning system of
15. The scanning system of
16. The scanning system of
17. The system of
18. The scanning system of
19. The scanning system of
21. The method of
22. The method of
23. The method of
24. The method of
25. The method of
26. The method of
27. The method of
rotating both the x-ray detector and the plurality of x-ray sources such that the plurality of x-ray sources and x-ray detector remain parallel to one another when rotated around the target.
28. The method of
29. The method of
simultaneously moving the x-ray sources and the x-ray detector longitudinally along the length of the target.
30. The method of
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The present application claims priority to U.S. Provisional Patent Application Ser. No. 62/434,147, entitled A Multi-Aperture Computed Tomography System, filed Dec. 14, 2016; U.S. Provisional Patent Application Ser. No. 62/445,539, entitled Equine Extremity X-ray Scanner, filed Jan. 12, 2017; and U.S. Provisional Patent Application Ser. No. 62/544,324, entitled Multi-Aperture Cone Beam CT System, filed Aug. 11, 2017, the entire disclosures of which are incorporated herein by reference in their entireties for all purposes.
The present application relates to multi-aperture scanning systems using overlapping cone-shaped computerized tomography (CT) scanning systems and fan-shaped beams for performing panoramic scanning.
Performing CT scans of body extremities such as arms, hands, legs and feet presents special difficulties. This is especially true in the veterinary context where the patient is a horse. Specifically, it has proven especially difficult to perform good CT scans of a horse's leg for a number of different reasons, including at least the following.
First, the geometry of a standing horse is extremely difficult to work with. Specifically, the separation distance between a standing horse's legs can be as little as 4 inches apart. In addition, the image of the leg and foot should be taken under natural loading during a natural standing pose. This provides little room for a veterinarian to safely maneuver X-ray equipment around the horse's legs. In addition, a typical exam for a performance horse can require 52 separate projection images taken for each of the 4 legs. Performing such an exam quickly is very difficult.
Second, traditional CT systems use only one X-ray source and a flat panel detector and must therefore acquire image data over multiple rotations to cover the entire volume of the leg or other object being imaged. Unfortunately, the X-ray source-to-detector distance must be increased to minimize the number of rotations required. This is difficult to achieve in tight geometries. Moreover, to fully illuminate the height of the detector, a significant source-to-image distance is required so that a standard cone-beam X-ray beam can expand enough to cover the rotating detector. Once again, it is difficult to work within such geometric constraints. It can also be unsafe both for the veterinarian and for the horse.
Third, despite taking a large number of images, important pathology such as stress fractures and micro-fractures can still be missed in a CT scan. To visualize such fractures, it is necessary to acquire the image with the source and detector lined up such that the crack or fracture in the bone is seen along its axis (i.e.: by lining up the seam of the crack with the X-ray beam).
Fourth, in conventional CT systems, the object to be imaged is typically placed equidistant between the source and the detector, and the source and detector are rotated around the object. This geometry is simply not possible to use with a standing horse's legs.
In short, traditional CT scanners that image whole-bodies are expensive to own and operate (especially if they image whole-bodies), and their geometries and rotational paths are completely unsuited to work with long narrow objects that are positioned close together (for example, the legs of a standing horse). Recently developed cone-beams systems have the advantage of acquiring images quickly with less expensive imaging components but have the disadvantage of being very large due to the need to rotate a flat-panel detector. Moreover, since the cone-shaped beam of the X-ray expands outwards towards the detector, the proximal side of the object being imaged will have a smaller region of exposure than the distal side. Lastly, requiring multiple rotations of the equipment increases the time to acquire the full image.
What is instead therefore desired is a system that would rapidly image a horse's leg (or any other object) in a fast period of time and within a small area of working space. As will be explained below, the present system provides solutions to these problems.
The present system provides CT scanning systems that can be used to rapidly image an elongated object such as a body extremity while working in tight geometries. In various aspects, a plurality of X-ray sources are used together with a single X-ray detector. Embodiments using both overlapping fan-shaped beams and overlapping cone-shaped beams are both contemplated, all keeping within the scope of the present system. Since the multiple X-ray beams overlap one another on the detector, the various X-ray sources are therefore preferably timed to fire sequentially.
As will be explained, separate positioning systems can be used for each of the X-ray detectors and the plurality of X-ray sources (which are preferably moved together as a unit). The advantage of such separate positioning/movement is that the panel of X-ray sources and the X-ray detector can be rotated or translated laterally to be kept parallel to face one another as the detector is moved between the horse's legs (which are positioned very close together). This can be achieved by rotating each of the X-ray source emitters and the X-ray detector about their own central vertical axes (at the same time that both the X-ray sources and the X-ray detector are also being rotated around the horse's leg).
In preferred aspects, the X-ray sources and the X-ray detector are rotated around the leg with the detector being positioned closer to the leg and the X-ray sources being positioned much farther from the leg. Thus, the X-ray detector preferably rotates around the leg or extremity with a much smaller radius, while the X-ray sources rotate around the extremity with a much larger radius. (In contrast, prior art systems place the target mid-way between the source beam emitter and the detector, with the emitter and detector connected together with a traditional C-arm).
In one preferred aspect, the present system provides a scanning system, comprising: a plurality of X-ray sources; an X-ray detector; a positioning system for rotating the X-ray detector in a first radius around the target; and a positioning system for rotating the plurality of X-ray sources in a second radius around the target; wherein the first radius is smaller than the second radius.
Optionally, the positioning systems for the X-ray detector and the X-ray sources can be connected together to simultaneously rotate the X-ray detector and the plurality of X-ray sources around the target. However, in other embodiments, the positioning systems for rotating the X-ray detector and the X-ray sources are not connected together such that the X-ray detector and the plurality of X-ray sources can be moved independently of one another.
In preferred aspects, the present system provides a control system for sequentially activating the X-ray sources. Optionally, the control system may activate different X-ray sources at the same time, but will not activate adjacent X-ray sources at the same time (i.e.: overlapping beams will not be activated at the same time).
Optionally, a longitudinal positioning system can also be used to simultaneously move the X-ray sources and the X-ray detector up and down along the length of the horse's leg (or along the length of some other long object being imaged).
In various optional aspects, the plurality of X-ray sources may either be mounted in a planar array, or mounted so as to be positioned in a spherical or cylindrical orientation with respect to the X-ray detector. In such aspects, the cone-shaped beams may even fully overlap with one another on the X-ray detector (and be fired sequentially).
The present system also includes a preferred method of scanning a target, comprising: providing a plurality of X-ray sources on a first support; providing an X-ray detector on a second support; and imaging a target by rotating the plurality of X-ray sources and the X-ray detector around the target, while sequentially emitting overlapping beams from the plurality of X-ray sources onto the X-ray detector. Using this method, the X-ray detector is preferably rotated in a smaller radius around the target than the plurality of X-ray sources are rotated around the target. Also using this method, the X-ray detector and the plurality of X-ray sources can optionally be moved independently of one another around the target.
In a first embodiment, the X-ray detector is a linear detector, and the X-ray sources are a line of emitters each emitting a fan-shaped beam. One advantage of a linear scanner is that it is much smaller than a traditional comparable flat-panel detector. This both reduces the diameter of the scanner and makes it possible to create a much longer scanning length. In addition, rotating the fan-shaped beams to be aligned with the length of the linear detector is advantageous since it avoids the need for spiral-path scanning (i.e.: moving along an object while also rotating around it). Therefore, an image of the horse's leg can be acquired in a single rotation if the linear detector and X-ray source array is long enough. This embodiment produces panoramic planar images of the target.
In a second embodiment, the X-ray detector is a planar detector, and the X-ray sources are a two-dimensional array of emitters each emitting cone-shaped beams that overlap one another on the detector. Using such a two dimensional matrix or array of individual X-ray sources that are fired in sequential order advantageously reduces the need for multiple scans and/or increases the X-ray source to detector distance. This embodiment produces Cone-Beam Computed Tomography (CT) images of the target.
Overall, the present system has the advantage of rapid image acquisition. Also, by using a multi-aperture X-ray source configuration, the present system reduces the volume and area occupied by the scanning system.
It is to be understood that the present scanning system encompasses features presented in different figures attached hereto, and that the attached figures are only exemplary and that possible features may be combined in different aspects of the present system, all as encompassed by the attached claims.
Referring first to
Optionally, both the X-ray sources 20 and the detector 30 are each mounted to positioning ring 40 such that they will fall over or move out of the way should the horse kick or accidently bump into them (thereby preventing damage to the horse's legs). For example, X-ray sources 20 and detector 30 could be mounted onto posts 21, 31 that are held to positioning ring 40 by magnets. Such magnets would be strong enough to support the X-ray sources and the linear detector during rotation, but weak enough such that they will give way if kicked by the horse. Alternatively, both X-ray sources 30 and linear detector 30 can be tethered such that cannot become flying objects should the horse accidently kick them.
In this panoramic imaging embodiment, the X-ray sources 20 are stacked one on top of another with their fan-shaped beams overlapping along the linear detector. As also seen, X-ray sources 20 can be mounted to a single support 21 that contains the necessary electrical feedthroughs and shielding, and provides mechanical support. An exemplary X-ray source emitter 20 can be a Toshiba D-0183S, made for intraoral dental applications. These Toshiba X-ray sources are 38 mm in diameter and 72 mm in length, and produce an X-ray beam with a maximum energy of 80 kV and 15 mA for 2 seconds. An exemplary linear X-ray detector 30 can be an X-Scan XB90808, manufactured by X-Scan of San Jose, Calif. This detector has a pixel size ranging from 0.2 mm, 0.4 mm, 0.8 mm or 1.6 mm. In optional aspects, it can be coated with a scintillating phosphor such as Gadolinium Oxysulfide, Cesium Iodide and Cadmium Tungstate to absorb X-rays and produce visible light that is detected by the sensors on detector 30.
A high-voltage power supply can be used to provide electrical power to X-ray sources 20 and linear X-ray detector 30. A computer operating console (not shown) can be used to manipulate and display the acquired images. The computer control system will also have patient registration, archiving and networking connectivity.
In various aspects, image detector 30 may have multiple columns of pixels and the columns of pixels can be summed together or read out individually after each exposure cycle. The image detector in this embodiment is known as a Time-Delay-Integration (TDI) camera. For example, the scanner can be rotated to advance a distance equal to one pixel or advanced a distance of several pixels to produce overlapping views.
As can be seen in
Unfortunately, it is not desirable to place X-ray sources 20 and X-ray detector 30 equidistantly around a horse's leg for at least the following reason. Doing so would increase the diameter of the circle of rotation of the X-ray source and detector, thereby increasing the distance and/or time to acquire the images. Instead, as illustrated in
As seen in
Since the fan-shaped beams will overlap on the linear detector, the X-ray sources 20A, 20B and 20C will be activated sequentially in rapid fire one after another. In preferred aspects, the X-ray sources are fired sequentially at a rate of 30 frames/second. It is to be understood, however, that in optional aspects, every third (or other) source produces a non-overlapping beam, therefore these third (or other) sources could instead be activated at the same time. This would have the advantage of increasing the speed of image acquisition. For example, sources 20A, 20C and 20E (see
Further limitations of scanning a horse's leg can be realized by viewing
For example, as seen in
For example, X-ray sources 20 may be moveable on a positionable support cart, trolley, mechanical or robotic platform 22 that can be independently navigated across the floor and X-ray detector 30 may also be moveable on a positionable support cart, trolley, mechanical or robotic platform 32 that can be independently navigated across the floor. Alternatively, X-ray sources 20 may be moveable with a robotic arm 24 while X-ray detector 30 may be moveable with its own robotic arm 34. In addition, each of X-ray sources 20 and X-ray detector 30 may be hand-held or otherwise moved by an operator using any means or system whatsoever.
In addition, since the movement of the X-ray sources 20 and the movement of the X-ray detector 30 can be “decoupled” (i.e.: each can be moved independently), then the present system can also optionally be used for tomosynthesis data collection. Tomosynthesis involves limited angle tomography with a lower number of discrete exposures. This reduces the radiation exposure and operating costs. In addition, the use of approximation algorithms and digital processing allows a 3D image set to be reconstructed so that individual 2D planes of focus can be viewed through the 3D data set.
It is to be understood, however, that these dimensions and parts are merely exemplary and that any suitable parts and dimensions can be used, all keeping within the scope of the present system. The support housing for X-ray sources 120 is preferably small enough to contain all nine X-ray sources, the necessary wiring, cooling means and shielding.
An advantage of using nine separate X-ray emitters 120 is that the duty cycle of each X-ray emitter is only 1/9th what would be required in the case of a single emitter. This advantageously reduces the heat loading on each of the emitters, and reduces the heat capacity for each emitter. The reduction in the source-to-detector distance also reduces the overall system power requirements.
In the cone-shaped beam embodiment of
Using a two dimensional array of X-ray sources 120 and a planar X-ray detector 130 having overlapping cone-shaped beams on the X-ray detector 130 has the advantage of ensuring that the proximal side of the target being imaged is exposed to sufficient X-rays, thereby reducing the need for additional scans and/or increasing the X-ray source to detector distance.
Unfortunately, although cone-shaped beam systems have advantages over fan-shaped beam systems, it is still difficult to fit a comparatively large detector 130 between a horse's legs (due to the width of the detector itself. To overcome this problem, the present system includes additional aspects in which positioning systems are provided to ease the detector 130 between the horse's legs without interrupting the scanning procedure.
Specifically,
A preferred method of movement of the X-ray source and the X-ray detector will also be explained below in relation to
Next,
The advantage of longitudinal positioning system 150 is that the full length of leg L can be imaged by a scanner having X-ray sources 120 and X-ray detector 130 that are much shorter than the full length of the leg to be imaged. It is advantageous to acquire CT images of the lower 27 inches of the horse's leg as this ensures that the carpal, fetlock, pastern and coffin joints (of the front legs) and the hock and fetlock joints (of the rear legs) are all imaged. When using a 12 inch high X-ray detector 30, it is therefore desirable to move the detector and X-ray sources up and down along the vertical height of the leg. For other extremity CT applications such as the human head, it is not necessary to provide eccentric source and detector rotation axes. Rather, both the X-ray sources and the detector can be rotated around the target.
It is to be understood that a longitudinal positioning system 150 becomes less needed when the X-ray sources 20 or 120 or 220 or 320 and X-ray detector 30 or 130 or 230 or 330 are taller, and more important when the X-ray sources and X-ray detector are shorter. In fact, simply making a sufficiently tall system 10 or 100 or 200 or 300 may avoid the need for a longitudinal positioning system 150 completely.
It is also to be understood that although longitudinal positioning system 150 is illustrated as providing vertical movement, the present system encompasses and longitudinal movement along the length of an elongated member (such as a limb, arm, or other object). Such movement may be vertical, horizontal movement in or any other angle.
Lastly,
First, in
Although
Cox, John D., Cantu, Gary R., Hueton, Iain
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