Weight gain rates of calves are surprisingly increased when the calves are fed a milk replacer containing brewers yeast and dextrose, the mixture providing from 0.25 to 5 pounds of dextrose per pound of brewers yeast. brewers yeast preferably is provided in the form of co-dried brewers yeast and brewers grains.

Patent
   5756132
Priority
May 03 1996
Filed
May 03 1996
Issued
May 26 1998
Expiry
May 03 2016
Assg.orig
Entity
Small
7
5
EXPIRED
1. A dry, water dispersible milk replacer for calves to promote weight gain, comprising, in combination with an edible carrier, dextrose and brewers yeast in the range of 0.25 to 5 pounds of dextrose per pound of brewers yeast.
14. A milk replacer for calves to promote weight gain comprising, in an aqueous dispersion, in combination with an edible carrier, dextrose and brewer's yeast in the range of 0.25 to 5 pounds of dextrose per pound of brewer's yeast.
8. A dry, water-dispersible milk replacer for calves to promote weight gain, comprising at least 3% by weight of dextrose, brewers yeast in the range of 0.25 to 5 pounds of dextrose per pound of brewers yeast, and an edible carrier including brewers grains.
12. Method of increasing the rate of weight gain of calves comprising feeding the calves a milk replacer comprising dextrose and brewers yeast in the range of 1 to 3 pounds of dextrose per pound of brewers yeast, and an edible carrier including brewers grains.
11. Method of increasing the rate of weight gain of calves comprising feeding the calves an aqueous dispersion of a milk replacer comprising an edible carrier and a mixture of dextrose and brewers yeast, the mixture providing from 0.25 to 5 pounds of dextrose per pound of brewers yeast.
10. A dry, water-dispersible milk replacer for calves to promote weight gain comprising a homogeneous dry mixture including the substantially free-flowing product resulting from drying together brewers yeast and brewers grains, the milk replacer containing from 7 to 15% of dextrose, and including brewers yeast in the ratio of from 1 to 3 pounds of dextrose per 100 pounds of brewers yeast.
2. The milk replacer of claim 1 including brewers grains, wherein the brewers yeast is admixed with the brewers grains to form a free-flowing product.
3. The milk replacer of claim 2 wherein said brewers yeast carried by said brewers grains is the free-flowing product resulting from drying said brewers yeast and brewers grains together.
4. The milk replacer of claim 2 including approximately equal amounts by weight of brewers yeast and brewers grains.
5. The milk replacer of claim 1 including one or more antibiotics selected from the group consisting of neomycin, and oxytetracycline.
6. The milk replacer of claim 1 including from 3 to 21 percent by weight of dextrose.
7. The milk replacer of claim 1 including from 7 to 15 percent by weight of dextrose.
9. The milk replacer of claim 8 comprising 7 to 15% by weight of dextrose, and containing brewers yeast in the range of 1 to 3 pounds of dextrose per pound of brewers yeast.
13. The method of claim 11 or claim 12 comprising feeding the calves sufficient milk replacer to provide from 13 to 95 grams of dextrose and about 6 to about 48 grams of brewers yeast per calf per day.
15. A milk replacer of claim 14 including in said dispersion brewer's grains.

The present invention relates to milk replacers employed in feeding very young calves to increase the rate of weight gain.

In the livestock industry, calves that are raised for veal and for herd replacement commonly are weaned from colostrum-rich cows milk to a nutrient-rich milk replacer within a few days following birth. Milk replacers are intended to replace whole milk and to thus provide an economic alternative to whole milk in the raising of the young animal. A variety of milk replacer compositions have been developed, including those sold commercially by Domain, Inc. under its Doboy® trademark. The latter milk replacers may include, as ingredients, dried milk, dried whey, dried whey protein concentrate, dextrose, and various vitamins and minerals. One calf milk replacer is described in De Laporte, U.S. Pat. No. 5,128,167.

Research has been ongoing for many years in an effort to determine how calves respond to various food ingredients and to formulate milk replacers to respond to the nutritive needs of pre-ruminants. A recent summary of milk replacer research is found in Trevor Tomkins, Sowinski, J. and Drackley, J. K., New Developments in Milk Replacers for Pre-Ruminants, 55th Minnesota Nutrition Conference & Roche Technical Symposium, 1994, pp. 71-82. This paper notes, on page 72, that the nutrient requirements of the calf are not well understood in relation to our understanding of the nutrient requirements of the young of other species.

D. C. Church, Digestive Physiology and Nutrition of Ruminants, Church, Dept. of Animal Science, Oregon State Univ., 1972, Vol. 3, p.122 reports that calf scours (diarrhea) has continued to be a problem with calves, and that although whole milk produces good veal calves, the protein to energy ratio may be too high for maximum weight. It has also been reported that weight gains of calves to eight weeks of age were increased by adding 3% cream or an equivalent amount of energy from glucose to 3.5% butterfat milk. J. H. B. Roy, The Calf Nutrition and Health, Penn. State Univ. Press, p. 100, reported that in France, a comparison of liquid diets containing 2.3-6.9% glucose and 0.5-3.5% fat showed that the highest weight gains were obtained when the highest concentration of glucose and of fat was used. Although retention of nitrogen was highest at the highest level of glucose, diarrhea was more frequent; this finding led to the recommendation that milk substitutes should contain not more than 2-3% glucose and a fat content of 2.5-3.5%. It has been reported that when more than 500 grams of lactose or glucose are given daily, there is a tendency for the calf to have diarrhea.

It has been suggested that direct-fed microbials such as yeasts may be beneficial in the feeding of calves. In Flaherty, M., in "Good Bugs' Concept Gaining Acceptance", Dairy Herd Management, March, 1994, pp. 78-80, it was pointed out that studies of calves fed various microorganisms provided inconclusive results. Some calves were found to gain weight; other tests showed no difference between those fed direct-fed microbials and those fed no microbials at all.

I have found that calves undergo a surprising rate of weight gain when fed a milk replacer that contains both dextrose and brewers yeast, the amount of dextrose varying from 0.25 to 5 pounds per pound of brewers yeast. The brewers yeast preferably is provided together with brewers grains, these ingredients desirably being dried together as by a Heil Triple Pass Grain Dryer or the like, so as to avoid to some extent the hygroscopic propensity of yeasts to clump and become non free-flowing. Desirably, the brewers yeast and dextrose ingredients of the invention are provided in combination with a dry, edible carrier preferably including brewers grains. The desired feeding rate for calves (after being weaned from colostrum-rich cows milk) is such as to provide from about 13 to about 95 grams of dextrose and from about 6 to about 48 grams of brewers yeast, per calf per day.

"Brewers yeast" is the dried, non-fermentative, non-extracted yeast of the botanical classification Saccharomyces resulting as a by-product from the brewing of beer and ale. It commonly contains not less than about 35% crude protein. "Brewers grains" means the dried extracted residue of barley malt alone or in mixture with other cereal grain or grain products resulting from the manufacture of wort or beer, and may contain pulverized dried spent hops in an amount not exceeding 3%. A reference to definitions of brewers yeast and brewers grains may be found in the 1996 official publication of the Association of American Feed Control Officials Incorporated ("AAFCO"), pp. 187 and 267. Brewers yeast and brewers grains may be combined by drying them together in a grain dryer to provide a dry, relatively non-hygroscopic product containing approximately equal amounts by weight of brewers yeast and brewers grains. The combined, dried brewers yeast/brewers grains product is available from the F.L. Emmert Co. under its product designation BGY-35. Brewers grains in this product provide the majority of the fiber, and the BGY-35 product referred to above contains up to about 9% of fiber by weight.

Desirably, the brewers yeast and dextrose (D-glucose) are combined, preferably by thorough mixing, with dry, edible ingredients that are dispersible in water such as dried milk, dried whey, dried whey protein concentrate, dried milk protein, lactose, lard and vegetable fat, together with various minerals and vitamins. A suitable dry carrier involves substantially any of the current commercially available calf milk replacers such as Doboy® Calf Pow-R TNT "Code 322" medicated milk replacer. Sufficient dextrose and brewers yeast are employed to provide the resulting milk replacer with brewers yeast at a concentration of about 1.5% to about 10.5% and preferably about 2.5% to about 7.5%. Dextrose is employed at the rate of about 0.25 to 5 pounds of dextrose, and preferably from about 1 pound to about 3 pounds of dextrose, per pound of brewers yeast. The concentration of dextrose in the dry milk replacer of the invention ranges from about 3% to about 21%, and preferably from about 7% to about 15%.

Although the product resulting from co-drying brewers yeast and brewers grains desirably contains about equal amounts by weight of each of these ingredients, the quantity of brewers grain may be varied as desired. Brewers yeast by itself is hard to handle in modern processing equipment, and sufficient brewers grains are preferably employed to lessen the hygroscopic nature of the yeast and to render the yeast/grain product substantially free flowing.

An appropriate calf milk replacer in accordance with the invention can be manufactured by thoroughly mixing 6.7 pounds of the co-dried brewers yeast and brewers grains product containing approximately 50% of each ingredient with 80 pounds of the Doboy® Calf Pow-R TNT milk replacer referred to above and 13.3 pounds of dextrose, the mixing continuing until the brewers yeast/brewers grains product is homogeneously mixed into the other dry ingredients to provide a water-dispersible dry product. To use the dried product, the product is mixed with water at the ratio of a cup or two of dried product per quart of warm water to form a dispersion, and is fed immediately after mixing.

A calf milk replacer of the invention was manufactured by homogeneously blending into Doboy® brand Calf Pow-R TNT Code 322 milk replacer (a product of Domain, Inc.), to which had been added 13.3 pounds of dextrose per 80 pounds of the commercial product, a sufficient quantity of co-dried brewers yeast and brewers grains ("BGY-35", a product of F. L. Emmert Co.) to provide the resulting product with approximately 2.0 pounds of dextrose per pound of brewers yeast. The Doboy® Calf Pow-R TNT medicated formula contains a dry mixture of dried milk, dried whey, dried whey protein concentrate, dried milk protein, lactose, lard, vegetable fat and dextrose, the concentration of dextrose being approximately 0.1% by weight of the commercial product. The commercial product includes various minerals including magnesium sulfate, manganese sulfate, zinc sulfate, ferrous sulfate, cobalt sulfate, sodium selenite, amino acids, ethylene diamine dihydriodide, and also oxytetracycline and neomycin. Because of the inclusion of the antibiotics, administration of this milk replacer should be discontinued 30 days prior to slaughter.

The Doboy® Calf Pow-R TNT product itself, into which had been blended 13.3 pounds of dextrose per 80 pounds of the commercial product, but without added brewers yeast or brewers grains, was employed as a dextrose-containing control. The milk replacer of the invention and the control milk replacer were fed twice daily to separate groups of calves at a rate providing 56 grams of dextrose per day to each calf.

Three groups of calves were selected, the first group weighing less than 90 pounds, the second group weighing from 90-99 pounds, and the third group weighing at least 100 pounds. Each group of calves was divided into two subgroups, the milk replacer of the invention being administered to one subgroup and the control milk replacer being administered to the other subgroup. The calves in each subgroup were randomly selected, and feeding was commenced a few days after birth and continued for 35 days. The initial and final weights of each calf were measured and are presented in the following table. In each group, the subgroup fed the milk replacer of the invention gained weight at a significantly higher rate than the calves fed the control milk replacer. The total weight gain of all of the calves fed the milk replacer of the invention was over 12% greater than the weight gain of calves fed the control milk replacer.

______________________________________
AVG AVG %
NO. START END AVG AVG
GROUP CALVES WGT WGT GAIN GAIN
______________________________________
Under 90 lbs.
Control 4 81.00 116.25 35.25 43.5
Invention
3 84.00 139.66 55.66 66.3
90-99 lbs.
Control 17 94.76 137.65 42.89 45.3
Invention
9 94.22 139.55 45.33 48.1
Over 100 lbs.
Control 15 110.33 153.66 43.33 39.3
Invention
23 108.65 156.13 47.48 43.7
Overall
Control 36 99.66 141.94 42.28 42.4
Invention
35 102.83 150.46 47.63 46.3
______________________________________

There appears to be no ready explanation for the surprising increase in weight gain of calves fed the milk replacer of the invention. Although I do not wish to be bound by the following, it may be speculated that the brewers yeast/brewers grains supplies B vitamins and higher levels of trace minerals than, for example, skim milk, and additionally supplies selenium and chromium. Moreover, the B-vitamin content of the brewers yeast/brewers grains may tend to counter the effect of dextrose in the milk replacer of the invention so as to inhibit the onset of scours. As pointed out above, prior researchers have indicated the difficulty in attempting to balance the ingredients of milk replacers so as to provide good results.

While a preferred embodiment of the present invention has been described, it should be understood that various changes, adaptations and modifications may be made therein without departing from the spirit of the invention and the scope of the appended claims.

Rebhan, Herbert

Patent Priority Assignee Title
10246729, May 12 2010 TIENSE SUIKERRAFFINADERIJ N V Process for the recovery of betaine from molasses
10940172, Jan 03 2017 PURINA ANIMAL NUTRITION LLC Methods of feeding animals phytogenic products
11213051, Jul 02 2014 PURINA ANIMAL NUTRITION LLC Milk replacer products containing halides and sources of hydrogen peroxide and methods of feeding same
11291220, Apr 24 2012 PURINA ANIMAL NUTRITION LLC Feeding methods and systems for young livestock animals using sensory compounds
11883451, Jan 03 2017 PURINA ANIMAL NUTRITION LLC Methods of feeding animals phytogenic products
7850989, Jun 12 2003 PROVIMI NORTH AMERICA, INC Critical care for neonatal calves
9668500, Apr 24 2012 PURINA ANIMAL NUTRITION LLC Feeding methods and systems for young livestock animals using sensory compounds
Patent Priority Assignee Title
4906641, Oct 27 1988 Anti-micturition composition and method
5128167, Mar 13 1990 Amylum, naamloze vennootschap Composition for the preparation of artificial calf milk and artificial calf milk prepared therefrom
5230902, Apr 27 1988 2458781 CANADA INC Undenatured whey protein concentrate to improve active systemic humoral immune response
5372811, Dec 03 1993 American Meat Protein Corporation Animal feed supplement containing co-spray dried plasma protein and amylase
5397589, Sep 02 1992 Ohio State University Research Foundation, The Preparation of calcium fortified powdered milk products with improved dispersibility
//
Executed onAssignorAssigneeConveyanceFrameReelDoc
May 02 1996REBHAN, HERBERTDOMAIN, INC ASSIGNMENT OF ASSIGNORS INTEREST SEE DOCUMENT FOR DETAILS 0080170048 pdf
May 03 1996Domain, Inc.(assignment on the face of the patent)
Date Maintenance Fee Events
Dec 18 2001REM: Maintenance Fee Reminder Mailed.
May 28 2002EXP: Patent Expired for Failure to Pay Maintenance Fees.


Date Maintenance Schedule
May 26 20014 years fee payment window open
Nov 26 20016 months grace period start (w surcharge)
May 26 2002patent expiry (for year 4)
May 26 20042 years to revive unintentionally abandoned end. (for year 4)
May 26 20058 years fee payment window open
Nov 26 20056 months grace period start (w surcharge)
May 26 2006patent expiry (for year 8)
May 26 20082 years to revive unintentionally abandoned end. (for year 8)
May 26 200912 years fee payment window open
Nov 26 20096 months grace period start (w surcharge)
May 26 2010patent expiry (for year 12)
May 26 20122 years to revive unintentionally abandoned end. (for year 12)