The invention concerns a device for automatically injecting injection liquids, comprising an axially divided housing, whereof the parts can be removably assembled. In a first part of the housing (13) is guided an axially mobile pressure pin (14) which can be driven in against a force accumulator (15), which can be locked once it has been driven in and can come out when the force accumulator (15) is released. In a second part of the housing (1) are arranged, axially mobile, an injection needle (4) maintained in a needle guide (5) and an ampoule (3). Said injection needle (4) maintained in the needle guide (5) can be axially mobile, relative to the ampoule (3), and has, on its side facing the ampoule (3), a perforation part (23) designed to perforate the ampoule (3). The second part of the housing (1) can be closed with a top (11) at its open end facing the first part of the housing (13).

Patent
   6743203
Priority
Jul 27 1999
Filed
May 03 2002
Issued
Jun 01 2004
Expiry
Jan 08 2021
Extension
165 days
Assg.orig
Entity
Large
131
10
all paid
1. A device for automatically injecting injection liquids, including an axially subdivided housing whose parts are detachably connectable, wherein an axially displaceable pressure pin is guided in a first housing part, which pin is capable of being inserted against a force accumulator and locked in the inserted position and extended upon relief of said force accumulator, and wherein an injection needle fitted within a needle guide and an ampoule are mounted in a second housing part in an axially displaceable manner, wherein the injection needle (4) is mounted so as to be displaceable in the axial direction relative to the ampoule (3) and, on its side facing the ampoule (3), is designed as a perforation piece (23) for the ampoule (3), characterized in that a helical spring (7) is arranged in the interior of the second housing part (1) between the housing end, including the passage opening for the injection needle (4) and the needle guide (5), that the needle guide (5), on its jacket, comprises at least one inwardly salient, axially resilient abutment piece (19) for the ampoule (3) and the needle guide (5), on its jacket, comprises at least one outwardly salient resilient abutment piece (20) which cooperates with an appropriate stop (21) of the second housing part, and that the second housing part (1), on its open end facing the first housing part (13), carries a thread or a bayonet capable of being screwed or latched with a counter-thread (10) or counter-bayonet, respectively, of the first housing part (13), or a sealing cap (11).
4. A device for automatically injecting injection liquids, including an axially subdivided housing whose parts are detachably connectable, wherein an axially displaceable pressure pin is guided in a first housing part, which pin is capable of being inserted against a force accumulator and locked in the inserted position and extended upon relief of said force accumulator, and wherein an injection needle fitted within a needle guide and an ampoule are mounted in a second housing part in an axially displaceable manner, wherein the injection needle (4) is mounted so as to be displaceable in the axial direction relative to the ampoule (3) and, on its side facing the ampoule (3), is designed as a perforation piece (23) for the ampoule (3), characterized in that a helical spring (7) is arranged in the interior of the second housing part (1) between the housing end, including the passage opening for the injection needle (4) and the needle guide (5), that the needle guide (5), on its jacket, comprises at least one inwardly salient, axially resilient abutment piece (19) for the ampoule (3) and the needle guide (5), on its jacket, comprises at least one outwardly salient resilient abutment piece (20) which cooperates with an appropriate stop (21) of the second housing part, and that the second housing part (1), on its open end facing the first housing part (13), carries a thread or a bayonet capable of being screwed or latched with a counter-thread (10) or counter-bayonet, respectively, of the first housing part (13), or a sealing cap (11), characterized in that the second housing part (1), on its end, including the passage opening for the injection needle (4), is closed by an elastic sealing disc (8), and characterized in that a piece (6) comprising a stop for the ampoule (3) is lockable in a second housing part region (9) that is designed to have an enlarged diameter, thus securing the ampoule (3) against falling out.
2. A device according to claim 1, characterized in that the second housing part (1), on its end, including the passage opening for the injection needle (4), is closed by an elastic sealing disc (8).
3. A device according to claim 1, characterized in that a piece (6) comprising a stop for the ampoule (3) is lockable in a second housing part region (9) that is designed to have an enlarged diameter, thus securing the ampoule (3) against falling out.

The invention relates to a device for automatically injecting injection liquids, including an axially subdivided housing whose parts are detachably connectable, wherein an axially displaceable pressure pin is guided in a first housing part, which pin is capable of being inserted against a force accumulator and locked in the inserted position and extended upon relief of said force accumulator, and wherein an injection needle fitted within a needle guide and an ampoule are mounted in a second housing part in an axially displaceable manner.

Devices of the initially mentioned kind have become known as autoinjectors. The known devices are pen-sized instruments which facilitate the injection of an emergency agent into the body in the event of an emergency situation. Autoinjectors are employed, for instance, in allergic emergency situations, e.g., in the event of insect or snake bites etc., but also in the military field, for instance, in order to rapidly counteract intoxications by C warfare agents. The known devices are usually designed as disposable devices, thus being disposed of after a one-time use.

From AT 303 251, an injection device is known, which comprises two housing parts capable of being screwed one into the other, the activator containing a spring-loadable pressure pin and the injector containing the ampoule as well as the injection needle as an inseparable unit. After having unlocked the spring-loaded pressure pin, the latter exerts a force on the piston plug of the ampoule, whereupon, at first, the ampoule is displaced in the axial direction together with the injection needle within the injector housing so as to cause the injection needle to penetrate into the body surface, and the liquid contained in the ampoule is subsequently set under such a high pressure that a sealing membrane provided between the ampoule and the injection needle will break, thus causing the liquid to be ejected. That known configuration, however, has the drawback that the broken membrane may obstruct the injection needle, thus preventing the rapid ejection of the injection liquid. Furthermore, that configuration constitutes a problem connected with the disposal of the autoinjector after use, since the injection needle projects out of the housing and, thus, constitutes a high risk of injury and infection.

The previously known autoinjectors, furthermore, have the drawback of rendering the safe storage and transportation of stand-by ampoules unfeasible. The ampoule can be inserted into the autoinjector only at works. Moreover, with the known autoinjectors, another whole autoinjector must always be taken along as a stand-by autoinjector.

The invention aims to provide a device of the initially defined kind, which can be disposed of without any risk of injury or infection and the disposal of which, in addition, is feasible in as environmentally safe a manner as possible by minimizing the number of parts to be disposed of. At the same time, the invention aims to provide a storing and transporting container for the ampoules, in which the filled glass ampoule can be stored over years in a safely protected and tightly sealed manner. In particular, it is to be feasible to carry along several ampoules containing different injection liquids and/or stand-by ampoules while minimizing the parts to be carried along. To solve this object, the device according to the invention essentially consists in that the injection needle fitted in the needle guide is mounted so as to be displaceable in the axial direction relative to the ampoule and, on its side facing the ampoule, is designed as a perforation piece for the ampoule, and that the second housing part, on its open end facing the first housing part, is closable by a sealing cap. By designing the injection needle as a perforation piece for the ampoule on its side facing the ampoule and mounting the injection needle so as to be displaceable in the axial direction relative to the ampoule, it is feasible to mount the ampoule in the interior of the second housing part, i.e., the injector, without being firmly connected with the injection needle. The injection liquid may, thus, be safely stored in the ampoule over years without the ampoule being firmly connected with any of the other structural components and the stability of the injection liquid being negatively affected. The use of an ampoule, moreover, substantially facilitates the manufacture of the injector part and, in addition, offers the advantage that a larger selection of different injection liquids will be available than with ready-made syringes.

It is only in use that the ampoule is displaced in the direction of the injection needle under the force of the pressure pin extended upon relief of the force accumulator, and pierced by the injection needle designed as a perforation piece on its side facing the ampoule. Thereby, any obstruction of the injection needle will be reliably prevented and it will be ensured that the injection liquid may leave the ampoule unhampered, after the injection needle has been pushed out of the injector housing and penetrated the tissue.

By making the second housing part closable by a sealing cap on its open end facing the first housing part, a storing and transporting container for the glass ampoule as well as a disposal container for the used injection needle and the empty ampoule is simultaneously provided. The housing part enclosing the ampoule and the needle may, thus be stored and transported separately from the activator part, the ampoule and the needle being protected in a breakage-proof manner and sealed in a bacteria-tight manner over years by means of the sealing cap. Thus, the carrying along of several different ampoules is, above all, facilitated. The activator part which can be carried along separately may be connected with the injector part containing the respective injection liquid according to demands. The carrying along of several activator parts is not necessary, since the activator is reusable.

The housing part enclosing the needle will be even more suitable for use as a disposal container, if the ampoule and/or the needle guide are advantageously mounted in a resilient manner. After the use of the autoinjector, the injector part is detached from the activator with the used injection needle projecting out of the injector housing automatically getting back into the interior of the housing due to the action of a resilient component. In this context, the configuration may be devised such that a helical spring is arranged in the interior of the second housing part between the housing end including the passage opening for the injection needle and the needle guide. Due to the fact that the second housing part, on its end including the passage opening for the injection needle, is advantageously closed by an elastic sealing disc, the needle-side end of the injector housing will always remain tight such that no sealing cap need be slipped on.

If the use of a resilient component acting on the needle guide or the ampoule is obviated, the injection needle may be pushed back into the housing after the use of the autoinjector by putting or screwing a sealing cap on that end of the second housing part out of which the used injection needle projects. The injector will be closed in any event on its open end facing the first housing part, i.e., the activator, thus forming a disposal container safely and sealingly receiving the used injection needle and the empty ampoule. Any injury or infection by the disposed parts is thereby excluded, and the number of parts to be thrown away is further minimized. As a result, the activator may be reused by inserting the pressure pin against a force accumulator and locking it in the inserted position and connecting the activator with a new injector. A new, unused injector will always be closed by a sealing cap prior to its first use, thus providing a storing and transporting container for the glass ampoule, by which the sterility of the ampoule and the needle unit will be safeguarded. Consequently, several injectors containing different injection liquids may, for instance, be carried along with the appropriate injector being connectable to the activator upon detachment of the sealing cap in an emergency case.

As already mentioned, the device according to the invention is devised such that the injection needle carrying the perforation piece for the ampoule is mounted so as to be axially displaceable relative to the ampoule by a needle guide. It is thereby ensured that the injection needle mounted so as to be axially displaceable by a needle guide, upon the action of force by the pressure pin on the piston of the ampoule, will, at first, be displaced in the axial direction and penetrate the tissue through the skin on the desired site, and the perforation piece of the injection needle will break the ampoule only after this, wherein the needle guide, on its jacket, advantageously comprises at least one inwardly salient resilient abutment piece for the ampoule and, furthermore, at least one outwardly salient resilient abutment piece which cooperates with an appropriate stop of the second housing part. The inwardly salient resilient abutment piece is dimensioned so as to offer a higher resistance against the force exerted by the pressure pin than the outwardly salient resilient abutment piece. As a result, the injection needle will, at first, penetrate the interior of the body while overcoming the force of the outwardly salient resilient abutment piece bending back in the direction towards the ampoule, whereupon the inwardly salient resilient abutment piece is being pushed inwardly into the needle guide as the perforation piece passes into the ampoule. Due to the outwardly salient resilient abutment piece cooperating with an appropriate stop of the second housing part in the transport and storage position, the needle guide can be precisely positioned and received within the housing in a manner secured in its position.

Advantageously, the device according to the invention is designed such that the sealing cap carries a thread or a bayonet capable of being screwed or latched with a counter-thread or counter-bayonet, respectively, provided on the open end of the second housing part.

In order to reliably prevent the ampoule from falling out of the second housing part after having been separated from the activator part, the configuration advantageously is devised such that a piece comprising a stop for the ampoule is lockable in a second housing part region that is designed to have an enlarged diameter, thus securing the ampoule against falling out. On account of the force of the expanding pressure spring acting on the needle guide, it is, thereby, safeguarded that neither the contaminated injection needle nor the then empty ampoule will fall out or be flung out of the second housing part.

Furthermore, the device according to the invention in a particularly advantageous manner is designed such that the counter-thread provided on the open end of the second housing part is capable of being screwed with a thread of the first housing part. This enables the counter-thread provided on the second housing part to be screwed with the sealing cap, on the one hand, and, upon detachment of the sealing cap, with the activator, on the other hand.

In the following, the invention will be explained in more detail by way of an exemplary embodiment schematically illustrated in the drawing. Therein, FIG. 1 illustrates the injector part of the device according to the invention with the sealing cap screwed on; FIG. 2 illustrates the injector part of the device according to the invention with the activator part screwed on, prior to the ejection of the injection liquid; FIG. 3 is a detailed view of FIG. 2; FIG. 4 shows a device of the invention according to FIG. 2 after the ejection of the injection liquid; FIG. 5 is a detailed view of FIG. 4; and FIG. 6 depicts the injector part of the device according to the invention with the sealing cap screwed on so as to be used as a disposal container.

FIG. 1 depicts the housing 1 of the injector part 2 of the device according to the invention. In the housing 1 are mounted in an axially displaceable manner an ampoule 3 and a needle guide 5 carrying the injection needle 4, a part 6 comprising a stop for the ampoule 3 being provided to secure said ampoule 3 against falling out. Furthermore, a helical spring 7 is arranged within the housing 1, whose function will be described farther below. The housing 1 is closed on its needle-side end by an elastic sealing disc 8. In the region 9, the housing 1 has a larger diameter as well as a thread 10 to enable a sealing cap 11 to be screwed thereon so as to provide a storing and transporting container for the filled glass ampoule 3.

In FIG. 2, the injector part 2 is screwed with the activator part 12. The activator part 12 is comprised of a housing 13 in which a pressure pin 14 is movably guided in an axially displaceable manner against the force of a spring 15. In the illustration according to FIG. 2, the pressure spring 15 is bent and the pressure pin 14 is locked in the extended position of the pressure pin. An actuation member 16 is provided on the rear end of the activator part 12 as a releasing means. The pressure pin 14 abuts on the ampoule piston 17, the ampoule 3, in turn, abuts on the resilient abutment piece 19 of the needle guide 5 in the region of the stepped collar 18. As is apparent, in particular, from FIG. 3, the needle guide 5 is formed with an outwardly salient abutment piece 20, which cooperates with a stop 21 of the housing 1 so as to ensure that the needle guide 5 is precisely positioned in the interior of the housing 1 and safely received in its position. From FIG. 3, it is, furthermore, apparent that the hollow needle 4 is designed as an injection needle 22 on its front end and as a perforation piece 23 on its ampoule-side end. In the illustration according to FIG. 3, the injection needle 4 is hermetically sealed by means of needle protection caps 24 and 25. Such needle protection caps may be used facultatively, in which case the elastic sealing disc 8 may be obviated.

After the actuation member 16 has been unlocked and axially lifted, the working stroke of the pressure pin 14 is released. The pressure pin 14 is moving forward in the axial direction as the spring 15 is being relieved and, with the interposition of the ampoule piston 17 which is not yet movable in the axial direction within the closed ampoule 3 and, furthermore, with the interposition of the resilient abutment piece 19, causes an axial displacement of the needle guide 5 such that the needle 4 emerges from the housing 1, while, at the same time, the outwardly salient resilient abutment piece 20 is being bent back in the direction towards the ampoule 3. In doing so, the elastic sealing disc 8 is perforated by the injection needle 22, whereby the spring 7 is compressed between the housing 1 and the needle guide 5. After the injection needle 4 has emerged from the housing 1, no further axial displacement of the needle guide 5 is feasible any more such that the force exerted on the ampoule piston 17 by the pressure pin 14 causes the resilient abutment piece 19 to become bent and then enables the ampoule 3 to move relative to the needle guide 5. In doing so, the ampoule side-end of the injection needle 4, which is designed as a perforation piece, pierces the ampoule seal 24 of the ampoule 3, thus enabling the injection liquid to be pressed out by the axial displacement of the ampoule piston 17 caused by the pressure pin 14.

FIG. 4 once again illustrates the device of the invention according to FIG. 2 with the ampoule 3 now being completely emptied, whereby it is apparent, in particular, from FIG. 5 how the abutments pieces 19 and 20, which offer differently high resistance forces to the force of the pressure pin 14, have become bent. The spring 7 is compressed in the instant case.

FIG. 6 depicts the injector part 2 screwed off the activator part 12 after use, with the injection needle 4 having been pushed back into the housing 1 by the pressure spring 7 acting on the needle guide 5. The housing 1 is again tightly closed on its needle-side end by the elastic sealing disc 8 such that the contaminated injection needle is located within the injector part 2 in a protected manner. The spring 7 additionally prevents the needle from moving so as to avoid a new perforation of the elastic sealing disc 8. The ampoule stop attached to part 6 and arranged within the housing prevents the ampoule 3 from falling out or being taken out. At the same time, the closing cap 11 is screwed in the thread 10 so as to enable also the other end to be tightly closed. In the main, this guarantees the optimum disposal and material separation while eliminating any risk of injury by the used injection needle at the same time.

Pickhard, Ewald

Patent Priority Assignee Title
10022503, Jan 24 2011 AbbVie Biotechnology Ltd; ELCAM MEDICAL AGRICULTURAL COOPERATIVE ASSOCIATION LTD Removal of needle shield from syringes and automatic injection devices
10105499, Jun 24 2013 PHARMA CONSULT GES M B H Activator for an autoinjector
10166344, Jun 10 2008 SHL MEDICAL AG Injection needle assembly
10220147, Aug 13 2015 Windgap Medical, Inc. Mixing and injection device with sterility features
10369277, Sep 12 2005 UNOMEDICAL A S Invisible needle
10376637, Feb 20 2008 Unomedical A/S Insertion device with horizontally moving part
10376652, Jan 21 2005 Novo Nordisk A/S Automatic injection device with a top release mechanism
10406291, Apr 04 2014 Novo Nordisk A S Autoinjector having needle shield triggering
10463805, Jun 10 2008 SHL MEDICAL AG Injection needle assembly
10485920, Jan 08 2015 Novo Nordisk A S Needle unit with a lockable needle shield and an injection device comprising such a needle unit
10532157, Apr 08 2016 University of Washington Ampule autoinjector systems and methods
10576206, Jun 30 2015 KALEO, INC Auto-injectors for administration of a medicament within a prefilled syringe
10688244, Dec 23 2016 KALEO, INC Medicament delivery device and methods for delivering drugs to infants and children
10695495, Mar 24 2015 KALEO, INC Devices and methods for delivering a lyophilized medicament
10709849, Jun 11 2013 Cilag GmbH International Guide for an injection device
10737028, Nov 23 2004 kaleo, Inc. Devices, systems and methods for medicament delivery
10780233, Jun 24 2013 Pharma Consult Ges.m.b.H. Activator for an autoinjector
10799634, Nov 12 2014 Novo Nordisk A S Method of manufacturing one of a range of autoinjectors
10799646, Jun 11 2013 Cilag GmbH International Injection device
10806867, Jan 24 2011 E3D AGRICULTURAL COOPERATIVE ASSOCIATION LTD Injector
10842938, Dec 23 2016 kaleo, Inc. Medicament delivery device and methods for delivering drugs to infants and children
10874804, Dec 21 2012 SHL MEDICAL AG Medicament delivery device
10898643, Feb 13 2008 UNOMEDICAL A S Sealing between a cannula part and a fluid path
10918791, Dec 04 2006 kaleo, Inc. Devices, systems and methods for medicament delivery
11007326, Jun 10 2008 SHL MEDICAL AG Injection needle assembly
11020526, Oct 04 2010 UNOMEDICAL A S Sprinkler cannula
11110261, Oct 19 2011 Unomedical A/S Infusion tube system and method for manufacture
11123492, Jun 11 2013 Cilag GmbH International Injection device
11154658, Aug 13 2015 Windgap Medical, Inc Mixing and injection device with sterility features
11167087, Aug 09 2019 KALEO, INC Devices and methods for delivery of substances within a prefilled syringe
11173255, Jun 11 2013 Cilag GmbH International Injection device
11197689, Oct 05 2011 UNOMEDICAL A S Inserter for simultaneous insertion of multiple transcutaneous parts
11260176, Dec 30 2015 Novo Nordisk A S Autoinjector having needle shield triggering
11311679, Jan 21 2005 Novo Nordisk A/S Automatic injection device with a top release mechanism
11426520, Jan 26 2011 kaleo, Inc. Medicament delivery devices for administration of a medicament within a prefilled syringe
11517674, Jun 30 2015 kaleo, Inc. Auto-injectors for administration of a medicament within a prefilled syringe
11565048, Jan 24 2011 Abbvie Biotechnology Ltd. Automatic injection devices having overmolded gripping surfaces
11590286, Nov 23 2004 kaleo, Inc. Devices, systems and methods for medicament delivery
11623051, Sep 17 2003 E3D AGRICULTURAL COOPERATIVE ASSOCIATION LTD Automatic injection device
11684767, Oct 19 2011 Unomedical A/S Infusion tube system and method for manufacture
11771830, Dec 23 2016 kaleo, Inc. Medicament delivery device and methods for delivering drugs to infants and children
11779710, Dec 21 2012 SHL MEDICAL AG Medicament delivery device
11786653, Mar 30 2010 Unomedical A/S Insertion device
11786662, Apr 08 2016 University of Washington Ampule autoinjector systems and methods
11793941, Jun 10 2008 SHL MEDICAL AG Injection needle assembly
11980742, Dec 29 2014 Novo Nordisk A S Drug delivery device with a hydraulic trigger mechanism
12070586, Jan 21 2005 Novo Nordisk A/S Automatic injection device with a top release mechanism
12178984, Oct 19 2011 Unomedical A/S Infusion tube system and method for manufacture
7717877, Jul 31 2003 WEST PHARMACEUTICAL SERVICES OF DELAWARE, INC Injecting apparatus
7785292, May 28 2004 Cilag GmbH International Injection device
7901377, May 28 2004 Cilag GmbH International Injection device
7985216, Mar 16 2004 DALI MEDICAL DEVICES LTD Medicinal container engagement and automatic needle device
8096978, Jan 21 2005 Novo Nordisk A S Automatic injection device with a top release mechanism
8132959, Aug 31 2007 Stryker Corporation Medical cement monomer ampoule cartridge for storing the ampoule, opening the ampoule and selectively discharging the monomer from the ampoule into a mixer
8137312, Jan 28 2003 INDIGO MED PTE LTD Detection apparatus and method
8162887, Jun 23 2004 AbbVie Biotechnology Ltd Automatic injection devices
8197443, Jan 28 2003 INDIGO MED PTE LTD Detection apparatus and method
8277414, May 28 2004 Cilag GmbH International Injection device
8303549, Dec 23 2005 UNOMEDICAL A S Injection device
8313463, May 28 2004 Cilag GmbH International Injection device
8313464, May 28 2004 Cilag GmbH International Injection device
8313465, May 28 2004 Cilag GmbH International Injection device
8317751, Apr 06 2005 Cilag GmbH International Injection device
8343110, May 28 2004 Cilag GmbH International Injection device
8366669, Apr 06 2005 Cilag GmbH International Injection device
8376998, Sep 17 2003 E3D AGRICULTURAL COOPERATIVE ASSOCIATION LTD Automatic injection device
8430850, Jul 03 2007 UNOMEDICAL A S Inserter having bistable equilibrium states
8439838, Jun 07 2006 UNOMEDICAL A S Inserter for transcutaneous sensor
8486003, Jul 10 2007 UNOMEDICAL A S Inserter having two springs
8562567, Jul 30 2009 UNOMEDICAL A S Inserter device with horizontal moving part
8603040, Jan 07 2003 Becton, Dickinson and Company Disposable injection device
8636704, Apr 29 2009 AbbVie Biotechnology Ltd Automatic injection device
8668670, Jun 23 2004 AbbVie Biotechnology Ltd Automatic injection devices
8679061, Jun 30 2006 AbbVie Biotechnology Ltd Automatic injection device
8708968, Jan 24 2011 ELCAM MEDICAL AGRICULTURAL COOPERATIVE ASSOCIATION LTD Removal of needle shields from syringes and automatic injection devices
8708970, Jun 10 2008 SHL MEDICAL AG Injection needle assembly
8734402, Jan 20 2009 Future Injection Technologies Limited Injection device
8758301, Dec 15 2009 AbbVie Biotechnology Ltd Firing button for automatic injection device
8790311, Jun 09 2006 UNOMEDICAL A S Mounting pad
8834419, Jun 19 2008 Cilag GmbH International Reusable auto-injector
8845594, Jun 19 2008 Cilag GmbH International Auto-injector with filling means
8858508, Jul 31 2003 WEST PHARMACEUTICAL SERVICES OF DELAWARE, INC Syringe with automatically triggered safety sleeve
8876775, Nov 16 2009 Needle safety cap
8939958, Jun 19 2008 Cilag GmbH International Fluid transfer assembly for a syringe
8945057, Aug 02 2006 UNOMEDICAL A S Cannula and delivery device
8968236, Apr 06 2005 Cilag GmbH International Injection device
9017287, Jun 23 2004 AbbVie Biotechnology Ltd Automatic injection devices
9028451, Jun 01 2006 Cilag GmbH International Injection device
9028453, Jun 19 2008 Cilag GmbH International Reusable auto-injector
9072833, Jun 01 2006 Cilag GmbH International Injection device
9108002, Jan 21 2005 Novo Nordisk A/S Automatic injection device with a top release mechanism
9180244, Apr 21 2010 AbbVie Biotechnology Ltd Wearable automatic injection device for controlled delivery of therapeutic agents
9186480, Jun 20 2007 UNOMEDICAL A S Apparatus for making a catheter
9186635, Mar 17 2009 STRYKER EUROPEAN HOLDINGS III, LLC Vacuum mixing device for bone cement and method for mixing bone cement in said device
9211379, Feb 28 2006 UNOMEDICAL A S Inserter for infusion part and infusion part provided with needle protector
9254373, Dec 22 2008 Modine Manufacturing Company Medical device comprising adhesive pad
9265887, Jan 24 2011 AbbVie Biotechnology Ltd Automatic injection devices having overmolded gripping surfaces
9278173, Dec 23 2005 UNOMEDICAL A S Device for administration
9320869, Jun 20 2007 Unomedical A/S Apparatus for making a catheter
9339610, Jan 24 2011 AbbVie Biotechnology Ltd; Elcam Medical Agricultural Cooperative Association Ltd. Removal of needle shield from syringes and automatic injection devices
9358346, Aug 31 2012 Cilag GmbH International Needle assembly for a prefilled syringe system
9415159, Mar 30 2010 UNOMEDICAL A S Medical device
9440051, Oct 27 2011 UNOMEDICAL A S Inserter for a multiplicity of subcutaneous parts
9486584, Jun 30 2006 Abbvie Biotechnology Ltd. Automatic injection device
9498582, Jul 23 2012 Terumo Kabushiki Kaisha Liquid administration device
9526845, Jul 02 2010 Sanofi-Aventis Deutschland GmbH Safety device for a pre-filled syringe and injection device
9533092, Aug 07 2009 UNOMEDICAL A S Base part for a medication delivery device
9561328, Apr 29 2009 AbbVie Biotechnology Ltd Automatic injection device
9566384, Feb 20 2008 UNOMEDICAL A S Insertion device with horizontally moving part
9616180, Jan 21 2005 Novo Nordisk A/S Automatic injection device with a top release mechanism
9642774, Sep 07 2011 STRYKER EUROPEAN HOLDINGS III, LLC Liquid container with predetermined breaking point
9649441, Apr 06 2005 Cilag GmbH International Injection device (bayonet cap removal)
9675757, May 28 2004 Cilag GmbH International Injection device
9675758, May 28 2004 Cilag GmbH International Injection device
9682194, Jun 19 2008 Cilag GmbH International Re-useable auto-injector with filling means
9687615, Jun 10 2008 SHL MEDICAL AG Injection needle assembly
9724127, Sep 27 2010 UNOMEDICAL A S Insertion system and insertion kit
9731080, Apr 06 2005 Cilag GmbH International Injection device
9757520, Jun 01 2006 Cilag GmbH International Injection device
9764090, Jun 23 2004 AbbVie Biotechnology Ltd Relating to automatic injection devices
9770558, Sep 27 2005 Cilag GmbH International Auto-injection device with needle protecting cap having outer and inner sleeves
9821117, Apr 21 2010 AbbVie Biotechnology Ltd Wearable automatic injection device for controlled delivery of therapeutic agents
9833579, Aug 19 2010 Novo Nordisk A S Medical injection device
9878102, Jan 24 2011 Abbvie Biotechnology Ltd. Automatic injection devices having overmolded gripping surfaces
9895493, May 28 2004 Cilag GmbH International Injection device
9950113, Nov 03 2010 Sanofi-Aventis Deutschland GmbH Needle assembly for the delivery of at least two medicaments
9999459, Mar 17 2009 STRYKER EUROPEAN HOLDINGS III, LLC Vacuum mixing device for bone cement and method for mixing bone cement in said device
ER2801,
ER3536,
ER9785,
ER9811,
Patent Priority Assignee Title
5658259, Oct 19 1995 MERIDIAN MEDICAL TECHNOLOGIES, INC Dental cartridge assembly auto-injector with protective needle cover
5695472, May 16 1994 Washington Biotech Corporation Modular automatic or manual emergency medicine injection system
5709668, Jan 16 1991 RANBAXY PHARMACEUTICALS, INC Automatic medicament injector employing non-coring needle
AT303251,
DE19532410,
DE4037418,
EP154593,
EP409365,
EP695554,
GB933976,
//
Executed onAssignorAssigneeConveyanceFrameReelDoc
Mar 14 2002PICKARD, EWALDPHARMA CONSULT GES M B H ASSIGNMENT OF ASSIGNORS INTEREST SEE DOCUMENT FOR DETAILS 0128610541 pdf
May 03 2002Pharma Consult Ges.m.b.H.(assignment on the face of the patent)
Date Maintenance Fee Events
Nov 29 2007M1551: Payment of Maintenance Fee, 4th Year, Large Entity.
Nov 22 2011M1552: Payment of Maintenance Fee, 8th Year, Large Entity.
Dec 01 2015M1553: Payment of Maintenance Fee, 12th Year, Large Entity.


Date Maintenance Schedule
Jun 01 20074 years fee payment window open
Dec 01 20076 months grace period start (w surcharge)
Jun 01 2008patent expiry (for year 4)
Jun 01 20102 years to revive unintentionally abandoned end. (for year 4)
Jun 01 20118 years fee payment window open
Dec 01 20116 months grace period start (w surcharge)
Jun 01 2012patent expiry (for year 8)
Jun 01 20142 years to revive unintentionally abandoned end. (for year 8)
Jun 01 201512 years fee payment window open
Dec 01 20156 months grace period start (w surcharge)
Jun 01 2016patent expiry (for year 12)
Jun 01 20182 years to revive unintentionally abandoned end. (for year 12)